severe combined immunodeficient mice

se·vere com·bined im·mu·no·de·fi·cient mice (SCID mice),

(se-vēr' kŏm-bīnd i-myū'nō-dē-fi'shent mīs),
Mice that lack both T and B lymphocytes and are used for transplantation and study of human lymphoid tissues resulting in a SCID-human mouse chimera.
See also: severe combined immunodeficiency, SCID mice.
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SCID or Severe Combined ImmunoDeficient mice are considered by many scientists to be the best available animal model for HIV because they lack their own immune system and therefore, permit human cell growth.

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