severe combined immunodeficiency disorder


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Related to severe combined immunodeficiency disorder: SCID, trimethylaminuria

severe combined immunodeficiency disorder (SCID)

A congenital immunodeficiency of both T and B LYMPHOCYTES. The condition is due to a genetic defect that causes a lack of the intracellular enzyme adenosine deaminase. As a result neither of these classes of lymphocytes can become immunologically functional and the affected child is gravely susceptible to infections of all kinds. X-linked SCID (SCID-X1) has now been successfully treated by gene therapy.
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- Preliminary results from an ongoing, multicenter study of X-linked Severe Combined Immunodeficiency Disorder (XSCID) suggest that gene therapy developed at Memphis, Tennessee-based St.
If so, it will be the first time British doctors have successfully corrected the gene defect that causes Severe Combined Immunodeficiency Disorder (SCID).
His wife Marie, 31, a teacher, said they were devastated when they learnt of their son's condition - Severe Combined Immunodeficiency Disorder.

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