severe and complicated malaria

severe and complicated malaria

A malignant clinical form of Plasmodium falciparum infection, which is usually caused by a result of delay in treatment.

Clinical features
• A change in behaviour, confusion or drowsiness;
• Impaired consciousness or unarousable coma;
• Multiple/recurrent convulsion;
• Deep breathing or respiratory distress;
• Difficulty in breathing or demonstrable pulmonary oedema, as may be seen radiologically;
• Circulatory collapse or shock ;
• Jaundice;
• Haemoglobinuria;
• Bleeding tendency;
• Prostration (i.e, generalised weakness so the patient cannot walk or sit up without assistance);
• Severe anaemia with or without congestive cardiac failure.
References in periodicals archive ?
Ours is a tertiary-care institute catering health services to the patients coming from overcrowded, lower socioeconomic society; hence, we encounter many cases of severe and complicated malaria who ultimately require higher therapeutic measures.
to identify the various clinical and laboratory parameters showing a prognostic significance in severe and complicated malaria.
24) Two cases of CM had peripheral smear negative but RDT was positive, this happens because in severe and complicated malaria, peripheral parasitaemia may be negative due to sequestration, whereas RDT provides evidence of antigenaemia.
Management of severe and complicated malaria in the intensive care unit.
Severe and complicated malaria treated with artemisinin, artesunate or artemether in Viet Nam.
Because of this potential problem, directors of hospital drug services should take into account the essential role of quinidine gluconate in treating patients with severe and complicated malaria before removing it from their formularies.
Other investigations were done if the patients fit the category of severe and complicated malaria as per WHO criteria.
DISCUSSION: Severe and complicated malaria is usually caused by P.
Association of HIV infection with the development of severe and complicated malaria cases at a rural hospital in Zimbabwe.
Each year, malaria directly causes nearly one million deaths and about 500 million clinical cases, of which 2 to 3 million constitute severe and complicated malaria (3,4).
While patients with uncomplicated malaria usually present with fever and non-specific symptoms, severe and complicated malaria is characterised by multiorgan involvement including acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) (8-10).
Full browser ?