sevelamer


Also found in: Dictionary, Wikipedia.
Related to sevelamer: lanthanum, Cinacalcet

sevelamer

 [sĕ-vel´ah-mer]
a phosphate binder used as the hydrochloride salt to reduce serum phosphorus concentrations in hyperphosphatemia associated with end-stage renal disease; administered orally.

sevelamer

/se·vel·a·mer/ (sĕ-vel´ah-mer) a phosphate-binding substance used as the hydrochloride salt to reduce serum phosphorus concentrations in hyperphosphatemia associated with end-stage renal disease.

sevelamer

[sĕvel′ahmer]
a phosphate binder used as the hydrochloride salt to reduce serum phosphorus concentrations in hyperphosphatemia associated with end-stage renal disease. It is administered orally.

sevelamer

A phosphate chelator used to reduce phosphorus in patients with end-stage renal disease and in chronic renal failure patients not requiring dialysis. It also reduces uric acid levels, and may be of use in patients with hyperuricaemia, uric acid nephrolithiasis and gout.

Adverse effects
Blood pressure lability (hypo- or hypertension), nausea, vomiting, dyspepsia, diarrhoea, constipation.

sevelamer

Renagel® Nephrology A chelator used to ↓ phosphorus in Pts with ESRD and in chronic renal failure Pts not requiring dialysis. See Chelation, End-stage renal disease.
References in periodicals archive ?
A phosphate binder, sevelamer helps to prevent low levels of calcium in the body (hypocalcemia) caused by elevated phosphorus.
Indian multinational pharmaceutical and biotech company Cipla (NSE: CIPLA) confirmed on Friday that its subsidiary InvaGen Pharmaceuticals Inc has received final approval from the US Food and Drug Administration (FDA) for Sevelamer Carbonate tablets, 800 mg.
Sevelamer can be variably brown, deep red, or light purple, thereby overlapping in appearance with both the BAS and Kayexalate (Figure 2).
Sevelamer versus calcium-based binders for treatment of hyperphosphatemia in CKD: a meta-analysis of randomized controlled trials.
Sevelamer hydrochloride is a non-absorbable polymer that contains neither aluminum, lanthanum, or calcium.
Systematic review of the clinical efficacy and safety of sevelamer in dialysis patients.
The introduction of sevelamer and lanthanum carbonate, 2 non-calcium binders, has been useful in reducing calcium levels in these patients.
calcium acetate and sevelamer (Renagel) are more expensive and not commonly used in children.
The treatment for hyperphosphatemia in patients with CKD is to use phosphate binders that include sevelamer and other calcium-based phosphate binders.
He was first author on a study in which 148 patients with moderate CKD were randomized to 9 months of calcium acetate, sevelamer carbonate, lanthanum carbonate, or placebo.
El 52% de los pacientes no tienen preferencias por los quelantes del fosforo y el farmaco que menos les gusta es el carbonato de lantano (27%) seguido de sevelamer, acetato calcico y carbonato calcico (4%).
Another chose to take the sevelamer less often, making "three months' worth of pills stretch to six months.