Isner was ahead by a service break
in the initial stages of the first set, breaking Djokovic in the third game when the Serb hit an unforced forehand error.
However, although Nadal seems to be almost unstoppable in his current frame of mind, he had to work hard against Stepanek, who saved eight set points in the first set and had two himself, before caving in to a single service break
in the second set.
Agassi started brightly, grabbing the first service break
, but after that he was simply steamrollered by an inspired Srichaphan who had never previously advanced beyond the second round of any Grand Slam event.
He raced to a service break
at the beginning of the second set, though it was clawed back by Pioline.
GREG RUSEDSKi, still smarting from his second round defeat in the Guardian Direct Cup in Battersea Park last week, stormed back with a win yesterday - in a match that didn't have one service break
After two sets without a service break
, top-ranked Djokovic broke Murray in the eighth game of the third set to seize momentum in the match.
Safina v Williams specials - first service break
: 6-4 Safina (S Jms/Bdrct), 8-13 Williams (Power); first ace: 13-8 Safina (S Jms/Bdrct), 4-9 Williams (S Jms/Bdrct); first double fault: 6-5 Safina (S Jms/Bdrct), 8-13 Williams (S Jms/Bdrct); first-set tie-break: 1-7 no (B365), 4 yes (B365); first-set winner: 7-4 Safina (S Jms/Bdrct), 4-7 Williams (Sky); tie-break in match: 4-11 no (B365, Boyles), 9-4 yes (B Sq, Lads); lose first set and win match: 9 Safina (Tote), 9 Williams (Tote); win first set and match: 3 Safina (Lads), 4-7 Williams (Lads, Tote); first Hawkeye challenge to be successful: 1-3 no (Boyles), 9-4 yes (Boyles).
Nadal's hopes of another epic five-set comeback were then crushed at the start of the third set when the Chilean won yet another service break
Leading 5-4, Sharapova wasted one match point on her opponent's serve but closed Chakvetadze out two games later to win the match with her fifth service break
Seppi hit back in the second set with a carbon copy of the first, racing into a 3-0 lead with a service break
before Henman finally held his serve in the fourth.
World number two Lindsay Davenport was a set up and a service break
Nishikori's form tailed off against the controlled Ferrer and he had a double service break
to hand the second set to the world number four.