serum bactericidal titre

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serum bactericidal titre

A term of art for the highest dilution of serum at which there is no visible growth of bacteria after 24 hours in subcultures from a serum inhibitory titre run, a rarely used method of determining the therapeutic adequacy of a particular antibiotic.
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meningitidis as a serum bactericidal titer of [greater than or equal to] 1:8 (4,7).
Three percent of children <18 years, and 19% of adults >19 years of age (median age 33 years), had serum bactericidal titers above or equal to the "protective" level (1:8) against this outbreak strain (Figure l, Table).
The importance of antiserogroup W135 serum bactericidal titers for protection is not well defined, but, extrapolating from serogroup C data, our results may indicate that 60%-80% of persons are susceptible to W135 disease.
For example, combination therapy for treatment of Pseudomonas aeruginosa pulmonary infections in cystic fibrosis patients achieved a cure rate of 89% if peak serum bactericidal titers were [greater than or equal to] 1:128 (28).