serotonin norepinephrine reuptake inhibitor

serotonin norepinephrine reuptake inhibitor

a class of antidepressant drugs the action of which is thought to result from inhibition of presynaptic reuptake of serotonin and norepinephrine.

ser·o·to·nin nor·ep·i·neph·rine re·up·take in·hib·i·tor

(serŏ-tōnin nōr-epi-nefrin rē-ŭptāk in-hibi-tŏr)
Class of antidepressant drugs the action of which is thought to result from inhibition of presynaptic reuptake of serotonin and norepinephrine.
References in periodicals archive ?
Psychotropic drugs were prescribed to 377; of those, 73% got a first-line treatment, either a selective serotonin reuptake inhibitor (SSRI) or a serotonin norepinephrine reuptake inhibitor (SNRI).
A third group took different antidepressants: venlafaxine (Effexor[R], a tetracyclic drug) and mirtazapine (Remeron[R], a serotonin norepinephrine reuptake inhibitor, or SNRI).
Serotonin norepinephrine reuptake inhibitor (SNRI) medications, such as Effexor, modulate both serotonin and norepinephrine.
At a meeting of the FDA's pediatric advisory subcommittee last month, the panel agreed that the class labeling changes for the selective serotonin reuptake inhibitors (SSRIs) and for venlafaxine, a serotonin norepinephrine reuptake inhibitor (SNRI), were reasonable.
CLARITY is a Phase II, 10-week, randomised, double-blind, placebo-controlled, multi-centre study designed to examine the efficacy and safety of adjunctive use of the product in patients with major depressive disorder who have an inadequate response to standard antidepressant therapy with either a selective serotonin reuptake inhibitor or a serotonin norepinephrine reuptake inhibitor.
Looking at drug classes, spending was greatest for (in order) erectile dysfunction drugs, bone resorption inhibitors, nonbarbiturate sleep aids, autoimmune treatments, statins, serotonin norepinephrine reuptake inhibitor antidepressants, antiplatelet agents, drugs for seizure disorders, atypical antipsychotics, and central nervous system stimulants.
The drug, a selective serotonin norepinephrine reuptake inhibitor (SNRI), has already been shown to be effective in relieving this bothersome menopausal symptom in a 12-week trial, which was reported last year.
Levomilnacipran, a serotonin norepinephrine reuptake inhibitor (SNRI), was reportedly discovered by Pierre Fabre and jointly developed with Forest Laboratories under a licensing agreement in the US and Canada.
Sibutramine (Meridia), a serotonin norepinephrine reuptake inhibitor, carries the risk of serotonin syndrome if prescribed along with an SSRI/SNRI and is best avoided in this context.
Instead, one should either switch to a combined serotonin norepinephrine reuptake inhibitor such as venlafaxine or duloxetine, or add bupropion or mirtazapine.
A retrospective data analysis from four clinical trials shows that patients taking Cymbalta(TM) (duloxetine hydrochloride), a serotonin norepinephrine reuptake inhibitor (SNRI) being studied for the treatment of depression, experienced a significantly lower incidence of sexual dysfunction compared to patients taking paroxetine, a commonly prescribed selective serotonin reuptake inhibitor (SSRI).
The drug, a selective serotonin norepinephrine reuptake inhibitor (SNRI), has been shown to be effective in relieving this menopausal symptom in a 12-week trial reported last year.

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