serotonin and norepinephrine reuptake inhibitor
Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.
Related to serotonin and norepinephrine reuptake inhibitor: SSNRI
serotonin and norepinephrine reuptake inhibitorAbbreviation: SNRI
An antidepressant medication (such as duloxetine or venlafaxine) that elevates mood by blocking neurons from taking up both norepinephrine and serotonin. Combined reuptake inhibitors differ from medications such as sertraline (Zoloft) or fluoxetine (Prozac), which are relatively selective serotonin reuptake inhibitors, and from tricyclic antidepressants, which primarily prevent the reuptake of norepinephrine by brain cells. SNRIs treat neuropathic pain as well as depression.
See also: inhibitor