Attack was defined when following criteria were fulfilled: 1) admission at first 72 hours with clinical symptoms (fever, abdominal pain, chest pain, arthralgia, serositis
, pleuritis, pericarditis, arthritis, peritonitis, myalgia, erysipelas-like erythema) 2) exclusion of other fever etiologies 3) fever should be [greater than or equal to] 37.
Moreover, investigation has shown pathologic findings consistent with appendicitis, serositis
, and pneumonia, he noted.
The remaining colon, small bowel, and stomach showed evidence of mild serositis
, but were grossly normal.
Familial Mediterranean fever (FMF) is an autosomal-recessive disorder (MIM 249100) characterized by recurrent attacks of fever and serositis
, affecting principally Sephardic Jewish, Armenian, Arab, and Turkish populations.
A symptom complex has been reported which may include a positive ANA, an elevated erythrocyte sedimentation rate, arthralgia/arthritis, myalgia, fever, serositis
, vasculitis, leukocytosis, eosinophilia, photosensitivity, rash and other dermatologic manifestations.
Arthritis may be absent at diagnosis, making the diagnosis more challenging, as the extra-articular features, such as serositis
, fever, anemia, or hepatosplenomegaly, often predominate.
Therefore, in clinical practice, serositis
findings in a patient receiving amiodarone can be ascribed to amiodarone after excluding other possible causes.
In an exploratory phase II trial, 175 patients whose primary disease manifestations were discoid rash, polyarthritis, or serositis
were randomized to receive prednisone plus abatacept, 10 mg/kg, or placebo by intravenous infusion on days 1, 15, and 29 and then every 4 weeks for 1 year.
Similarly, Wang, et al, showed only five of 10 patients with lupus serositis
had a pleural-fluid-to-serum-ANA ratio of 1.
A drug-induced lupus-like syndrome may present with arthralgias, myalgias, fever, and serositis
but is distinguished from systemic lupus erythematosus by several characteristics.
Herein we describe a unique proliferative serositis
associated with E bieneusi infection of mesothelial cells in immunodeficient rhesus macaques.
The first onset of symptoms included oral ulcers, multiple serositis
, multiple inflammatory synovitis, urine protein levels of 1.