Alpha 1--acid glycoprotein (AGP) is an acute phase reactant protein reported in the seromucoid
portion of the serum (SELTING et al., 2000; WINKEL et al., 2015).
Affected animals show clinical symptoms like seromucoid
nasal discharges, nasal granuloma with miliary/cauliflower like unilateral/bilateral growths (cattle) and serous nasal discharge and pinhead sized granular eruptions (buffaloes).
The diagnosis and classification of the types of otitis media were based on: (i) clinical data of otalgia and otomicroscopic findings of opacity and bulging of the intact tympanic membrane for AOM; (ii) a wet, swollen and contourless eardrum for perforated AOM; (iii) evidence of seromucoid
effusion in the middle ear (completely filled or air-fluid level or bubbles), with an intact tympanic membrane without symptoms of acute infection for OME;  and (iv) evidence of a perforation or cholesteatoma with or without purulent discharge for CSOM.
Nasal symptoms may be prominent, with nasal discharge and stertorous respiration 3 Parainfluenza Paramyxovirus Sheep and Mostly associated goats with enzootic pneumonia 4 Caprine Retrovirus Neurologic Lymphocytic mastitis arthritis disease in and hard firm udders encephalitis kids and along with chronic virus arthritis wasting in adults 5 Ovine Oncogenic Sheep Chronic emaciation, progressive retrovirus of weakness, dyspnea, pneumonia subfamily lymphoproliferative (maedivisna) Lentiviridae pneumonia, meningeal arteritis with encephalitis, nonsuppurative arthritis, and lymphocytic mastitis Enzootic Retrovirus Sheep and Signs of inspiratory 6 nasal tumors, goats dyspnea along with ovine seromucoid
nasal pulmonary discharge adenomatosis (Jaagsiekte) 7 Enzootic M.
The right-sided mass had previously ruptured into the right nostril, draining a seromucoid
Clinical signs appeared in 26 calves, 6-7 months old, and consisted of fever (39.4[degrees]-40.1[degrees]C), cough, accelerated pulse and breath, seromucoid
nasal discharge, and leukopenia.