Historically, most meningococcal disease outbreaks on university campuses in the United States were caused by serogroup
Meningococcal disease - a bacterial disease also known as meningitis - has many strains, with each one being called a specific serogroup
; the five major strains are serogroups
A, B, C, W and Y.
Currently, there are two different types of vaccines available to help protect against the five vaccine-preventable serogroups
of meningococcal meningitis--A, C, W, Y, and B.
meningitidis isolates were requested for serogroup
typing at the Georgia Public Health Laboratory as part of Active Bacterial Core surveillance.
Due to results of penicillin E-test, distribution of serotype/serogroups, 13 strains having low-level resistance were determined to be in serogroup
Genomic Epidemiology of Hypervirulent Serogroup
W, ST-11 N.
There is widespread agreement about the severity of invasive meningococcal disease, the peaks of incidence in infancy and late adolescence, a 10% case fatality rate, an additional 10%-15% morbidity, and the limited number of cases (in the United States) to be prevented by adolescent immunization despite serogroup
B being the most common.
Of note, since 2002, serogroup
C prevalence has overtaken serogroup
B cases in most regions of Brazil.
These data, which were reviewed by the CHMP, demonstrate that the benefits of Trumenba are its ability to induce protective serum bactericidal antibody responses to diverse meningococcal serogroup
B strains expressing fHBP variants that are representative of MenB strains causing invasive disease, and that TRUMENBA is a well-tolerated vaccine.
These data demonstrate that the benefits of TRUMENBA are its ability to induce protective serum bactericidal antibody responses to diverse meningococcal serogroup
B strains expressing fHBP variants that are representative of MenB strains causing invasive disease and that TRUMENBA is a well-tolerated vaccine.
However, resistance pattern to the rest of the antibiotics varied widely among serogroups
D showed the highest variability from 20% to 97% resistance to chloramphenicol, tetracycline, trimethoprim-sulphamethoxazole, and ampicillin antibiotics.
In the 8MM in 2015, 43.37% of the laboratory-confirmed incident cases of IMD are serogroup
C disease, 36.46% are serogroup
B disease, 5.25% are serogroup
Y disease, and 14.98% are disease caused by other serogroups