seroconversion


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seroconversion

 [se″ro-kon-ver´zhun]
the change of a serologic test from negative to positive, indicating the development of antibodies in response to infection or immunization.

se·ro·con·ver·sion

(sē'rō-kon-ver'zhŭn),
Development of detectable specific antibodies in the serum as a result of infection or immunization.

seroconversion

(sîr′ō-kən-vûr′zhən)
n.
Development of antibodies in blood serum as a result of infection or immunization.

se′ro·con·vert′ (-vûrt′) v.

seroconversion

Immunology The development of antibodies detectable in the serum, after exposure to a particular organism or antigen, in a person who was previously immunologically 'naive' for–ie, previously unexposed to a particular antigen; seroconversion may indicate current infection–and transmissibility of a pathogen–eg, HIV-1–seroconversion to p24 and/or p41 antibody production or HBV–seroconversion to surface antibody-HBsAb or e antibody–HBeAb production. See Seropositive. Cf Seronegative.

se·ro·con·ver·sion

(sēr'ō-kŏn-vĕr'zhŭn)
The process by which, after exposure to the etiologic agent of a disease, the blood changes from a negative to a positive serum marker for that specific disease.

Seroconversion

The change from HIV-negative to HIV-positive status during blood testing. Persons who are HIV-positive are called seroconverters.
Mentioned in: AIDS Tests

se·ro·con·ver·sion

(sēr'ō-kŏn-vĕr'zhŭn)
Development of detectable specific antibodies in the serum due to infection.
References in periodicals archive ?
aureus had notably lower seroprotection and seroconversion rates to the B strain (12% vs.
(7) Detection of HCV RNA by PCR, or derivative methods such as transcript-mediated amplification (TMA), permits the identification of acutely infected donors before their seroconversion for antibody to HCV, who would have been missed by conventional serological tests.
The seroconversion rate was relatively low: over a median follow-up of three years, 4.3 percent of spouses became HIV-positive.
Seroconversion can occur as late as 6 months after exposure, while detectable levels of viraemia and p24 antigenaemia develop over the first 3--4 weeks of infection.
In HBeAg-positive patients the primary goal is sustained HBeAg seroconversion, while in HBeAg-negative patients the goal is sustained HBV DNA suppression.
On May 24, 2008, the New York City Department of Health and Mental Hygiene informed NYSDOH of a confirmed HCV seroconversion in one patient receiving chronic hemodialysis treatment at the unit.
By the end of the study period in 2006, "there was no evidence of any excess mortality to 5 years from seroconversion in any age group," Mr.
All workers present at the bridge site at any time during 1-30 August comprised the full cohort in which we conducted a study to evaluate risk factors for histoplasmosis, including age, residency within the Mississippi or Ohio river valleys, preexisting illness, and specific job duties in persons with acute HC seroconversion. We screened workers with fever and respiratory symptoms for histoplasmosis infection by physical exam, urinary testing for H.
Other independent risk factors for seroconversion included having a new sexual partner in the 4 months before HSV-2 seroconversion (hazard ratio of 2.6) and having 12 or fewer years of education (hazard ratio of 2.8).
To assess seroconversion status, we included 90 patients that had either received the full immunization course ([greater than or equal to] 3 doses) or had converted to anti-HBs seropositivity mid-course after receiving at least one vaccine dose.
Chris, a 40-year-old Chicagoan, also attributes his seroconversion to a crisis of self-esteem but thinks it had little to do with homophobia.
The new estimates, extrapolated from several studies that measured seroconversion rates in various samples of the city's gay/bi male population, were hashed out over nearly five hours January 19.