If there is < 50% reduction in the LDL-C level while taking maximally tolerated statin and ezetimibe therapy, adding a bile-acid sequestrant
can be considered, as long as the TG level is not > 300 mg/dL (ie, bile-acid sequestrants
can elevate the TG level significantly).
The standard patient preparation requires the suspension of bile acid sequestrants
and antidiarrheal drugs one week prior to the first appointment because of interference with test results and requires fasting at least 4 hr before taking the SeHCAT capsule (GE Healthcare).
This fatal case of ischemic colitis showed abundant Kayexalate (arrow) and bile acid sequestrant
(BAS) resins (bracket, asterisks) at the perforation site.
Sevelamer is known to bind negatively charged bile acids, thus acting as a bile acid sequestrant
that can lower low-density lipoprotein concentrations .
Other agents such as phenobarbital and the bile acid sequestrant
, cholestyramine, have been studied in a small randomised trial in France, with no significant benefit.
Glucono delta-lactone (GDL) is a naturally occurring food additive used as a sequestrant
, an acidifier, or a curing, pickling or leavening agent.
La violence que commet le frere aine de Yuemei contre elle en la sequestrant
sur ordre du pere a cause de sa liaison amoureuse avec un officier d'aviation est devolue a Zao, qui, ronge par ses obsessions erotiques a la recherche de l'epanouissement de Lan-ying, lui interdit de sortir.
Since 2000 Welchol, a bile acid sequestrant
, has been indicated--alone or in combination with a statin--for the reduction of elevated LDL-C levels in patients with primary hypercholesterolemia.
Prescriptions were ranked as follows: statins (70.9%), fibrates (27.5%), bile acid sequestrant
resins (0.9%), and others (0.7%), all at low dosage levels.
The committee has examined the safety aspects of antimicrobial solutions which are prepared from acetic acid and octanoic acid together with hydrogen peroxide using HEDP as a sequestrant
or stabilizer and strongly opined that they would not pose a safety concem.
Alkaline cleaners are specifically formulated chemical blends consisting of alkaline salts, wetting agents, and sequestrant
The FDA accords citric acid the status of generally recognized as safe (GRAS) as a food substance and GRAS limited only by GMP as a sequestrant
. The FAO/WHO approves it for use in foods without limitation.