appears to increase the likelihood of an HIV-infected patient experiencing neutropenia.
Concurrent chemo-RT improves 5 years survival by an additional 5% as compared to sequential chemotherapy
followed by RT.
and intensity-modulated radiation therapy in the management of locoregionally advanced nasopharyngeal carcinoma: experience of 370 consecutive cases.
4) Previously reported series of surgical salvage have generally included patients treated with suboptimal primary therapy (Radiotherapy alone or sequential chemotherapy
and radiotherapy), while subsequent randomized trials.
70,71] Treatment modalities included chemotherapy alone, neoadjuvant chemotherapy followed by cystectomy, cystectomy followed by adjuvant chemotherapy, cystectomy alone, transurethral resection of bladder tumour (TURBT) alone, radiotherapy alone and finally concurrent or sequential chemotherapy
5 percent of patients receiving sequential chemotherapy
It is generally accepted that patients with metastatic disease do benefit from systemic chemotherapy resulting in response rates of about 50% with combination chemotherapy, a median progression-free survival of about 9 months and a median overall survival approaching 2 years with the use of sequential chemotherapy
The 10-year overall survival rate of women who received sequential chemotherapy
followed by tamoxifen was 68%, compared with 62% with concurrent chemotherapy plus tamoxifen and 60% for tamoxifen alone.
Cell proliferation in malignant angioendothelioma during sequential chemotherapy
Other risk factors for febrile neutropenia included low pre-treatment levels of white blood cells and sequential chemotherapy
with adriamycin followed by cyclophsphamide, methotrexate and fluorouracil.