9-Sep

(redirected from septin-9)

9-Sep

A gene on chromosome 17q25 that encodes septin 9, a member of the septin family of nucleotide-binding proteins, which are required for cytokinesis, organisation of submembranous structures, neuronal polarity and vesicle trafficking. SEPT9 is a candidate for ovarian tumour suppressor gene.

Molecular pathology
SEPT9 mutations cause hereditary neuralgic amyotrophy (neuritis with brachial predilection). A translocation between SEPT9 and MLL on chromosome 11 results in acute myelomonocytic leukaemia.
References in periodicals archive ?
Wandell, Michael; Ramsey, Scott: Screening for Colorectal Cancer with a Blood Test: Projected Effectiveness and Cost-Effectiveness of a Novel Plasma Methylated Septin-9 DNA (mSEPT9) Assay.
0 84 Table 36: Detector C SWOT Analysis, 2013 85 Table 37: Product Profile - ColoSure 88 Table 38: ColoSure SWOT Analysis, 2013 88 Table 39: Product Profile - MS9 90 Table 40: MS9 SWOT Analysis, 2013 91 Table 41: Septin-9 CRC Screening Marketed Laboratory-Developed Tests 91 Table 42: Product Profile - ColoVantage/Septin-9 92 Table 43: ColoVantage/Septin-9 SWOT Analysis, 2013 93 Table 44: Product Profile - Tumor M2-PK Stool Test/2-in-1 Quick Test 95
Company Licenses Septin-9 DNA Methylation Biomarker from Epigenomics