7-Sep

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7-Sep

A gene on chromosome 7p14.2 that encodes septin 7, a member of the septin family of nucleotide-binding proteins, which are required for cytokinesis. Septin 7 is linked to suppression of glioma cell growth and is a requirement for the association of centromere-associated protein E with the kinetochore.

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found that the activity of myosin II was reduced by septin 7, which could hinder GLUT4 storage vesicle and fusion with the plasma membrane, reduce glucose uptake into podocytes, and further cause insulin resistance [24].

Tienari et al., "Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion," Experimental Cell Research, vol.

Association between MYH9 and APOL1 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in Patients with Type 2 Diabetes in a Chinese Han Population

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