each daily time point or patient-day) would be considered an independent clinical indicator to alert frontline neonatologists to perform sepsis workup before signs and symptoms became clinically apparent.
In addition, there were 63 episodes for which CD64 levels were increased in asymptomatic infants who did not require sepsis workup and recovered spontaneously without the need for antimicrobial treatment (i.
involved complete blood counts along with haematological score (Rodwell's) and microbial culture.
Recommendations for clinical practice Women who chose epidural analgesia in this study had a markedly increased risk of intrapartum fever; likewise, their newborns were more likely to require a sepsis workup and antibiotic treatment.
Study design and validity This study is a retrospective analysis of data from the ACT trial as it relates to epidural use, neonatal sepsis workups, and antibiotics.
Taken together, the findings in the current study "are consistent with relative immaturity at 36-38 weeks (regardless of lung maturity), compared with 39-40 weeks, and lower threshold for admission to the NICU and for invasive sepsis workups
(suspected sepsis)," the investigators wrote.
Neonatal sepsis workups
in babies =2000 grams at birth: a populationbased study.