sentinel lymph node


Also found in: Acronyms, Wikipedia.

sentinel lymph node

the first lymph node to receive lymphatic drainage from a malignant tumor; the sentinel nodes are identified as the first to take on a radionuclide or dye injected into the tumor; increasingly used in operations for melanoma and breast cancer; if the sentinel nodes are free of metastasis, more distal nodes are usually also free.
See also: signal lymph node.

sen·ti·nel lymph node

(sen'ti-nĕl limf nōd)
The first lymph node to receive lymphatic drainage from a malignant tumor; the sentinel node is identified as the first to take up a radionuclide or dye injected into the tumor; increasingly used in operations for melanoma and breast cancer; if the sentinel node is free of metastasis, more distal nodes are also free.
See also: signal lymph node

Sentinel lymph node

The first lymph node to receive lymph fluid from a tumor. If the sentinel node is cancer-free, then it is likely that the cancerous cells have not metastasized.
Mentioned in: Vulvar Cancer
References in periodicals archive ?
Burelli et al., "Morbidity comparison of sentinel lymph node biopsy versus conventional axillary lymph node dissection for breast cancer patients: results of the sentinella-GIVOM Italian randomised clinical trial," European Journal of Surgical Oncology, vol.
Table 5 shows the number of nonsentinel lymph nodes obtained following a positive sentinel lymph node biopsy.
(14) Sentinel lymph nodes will be covered in Part Two of this article.
Intraoperative lymphatic mapping and sentinel lymph node biopsy using radioactive tracer in gastric cancer.
Sentinel lymph node biopsy in cutaneous melanoma: analisis of 240 consecutive cases.
Evaluation of intraoperative scrape cytology for sentinel lymph node biopsy in patients with breast cancer.
The site of the sentinel lymph node (hot spot) was marked on the skin.
The sentinel lymph node concept in prostate cancer - first results of gamma probe-guided sentinel lymph node identification.
Thompson et al., "Improved sentinel lymph node localization in patients with primary melanoma with the use of radiolabeled colloid," Surgery, vol.
Hillemanns, "Validation of the accuracy of the sentinel lymph node procedure in patients with vulvar cancer: results of a multicenter study in Germany," Gynecologic Oncology, vol.
"The declipseSPECT technology and its intraoperative use for navigated sentinel lymph node dissection will enable safer surgeries, and less invasive procedures.
The study demonstrates that radiolabeled dextran cysteamine mannose might prove a successful radiopharmaceutical for sentinel lymph node detection in future clinical applications.