Risk categorisation system Category Risk profile Check-up frequency 0 No sensory Once a year neuropathy 1 Sensory neuropathy
Once every 6 months 2 Sensory neuropathy
Once every 3 months and signs of peripheral vascular disease and/or foot deformities 3 Previous ulcer Once every 1 - 3 months
The incidence of adverse events was generally similar in older and younger patients, with peripheral sensory neuropathy
, fatigue and anemia appearing to be more common among patients age 60 or older.
Patients receiving oxaliplatin injection plus 5-FU/LV and requiring oral anticoagulants may require closer monitoring -- The most common adverse reactions in patients with Stage II or III colon cancer receiving adjuvant therapy were peripheral sensory neuropathy
, neutropenia, thrombocytopenia, anemia, nausea, increase in transaminases and alkaline phosphatase, diarrhea, emesis, fatigue, and stomatitis.
The most common adverse events were nausea (38 percent), peripheral sensory neuropathy
(38 percent), fatigue (34 percent), fever (33 percent) and diarrhea (29 percent)
A discussion of the co-morbidities associated with diabetic foot pathology, including sensory neuropathy
, painful neuropathy, peripheral vascular disease, food wounds, and more
Relapsed MM and MCL: In the integrated analysis of 1163 patients in phase 2 and 3 studies, the most commonly reported adverse events were asthenic conditions (including fatigue, malaise, and weakness) (64%), nausea (55%), diarrhea (52%), constipation (41%), peripheral neuropathy NEC (including peripheral sensory neuropathy
and peripheral neuropathy aggravated) (39%), thrombocytopenia and appetite decreased (including anorexia) (each 36%), pyrexia (34%), vomiting (33%).
In the randomized metastatic breast cancer study, the most important adverse events included alopecia (90%), neutropenia (all cases 80%; severe 9%), sensory neuropathy
(any symptoms 71%; severe 10%), asthenia (any 47%; severe 8%), myalgia/arthralgia (any 44%; severe 8%), anemia (all 33%; severe 1%), infections (24%), nausea (any 30%; severe 3%), vomiting (any 18%; severe 4%), diarrhea (any 27%; severe <1%), and mucositis (any 7%; severe <1%).
The most common adverse events of any grade occurring in more than 30 percent of patients were neutropenia, nausea, peripheral sensory neuropathy
, fatigue, vomiting, diarrhea, insomnia, bone pain, constipation and hair loss.
associated long-terme etretinate (ET) therapy.
The diagnostic tool, the peripheral sensory neuropathy
test, scans the foot to look for major skin breaches and, using "pressure mapping", detects the loss of sensation associated with ulceration.
The diagnostic tool - the peripheral sensory neuropathy
test - scans the foot to look for major skin breaches and, using what's called pressure mapping, detects the loss of sensation associated with ulceration.
It is likely that the chemotherapy caused a sensory neuropathy
of her bowels that caused her constipation and subsequent overflow incontinence.