1 day after treatment with colchicine), a
sensitizing dose of 2% DNCB about 0.1ml dissolved in acetone was applied on the right side of skin of thorax region below arm of each mice in treated groups.
1 day after treatment with ketoprofen), a
sensitizing dose of 2% DNCB in acetone was applied to mice in both control and ketoprofen treated groups.
It was anticipated that only the group of mice administered with 10 mg/kg showed a significant reduction in the mean values of skin thickness when compared with the mean values of other groups after applying a
sensitizing dose of DNCB (Table III).
right flank region for
sensitizing dose and left flank for challenge dose.