sensitizing dose

sen·si·tiz·ing dose

in experimental anaphylaxis, the antigenic inoculum that renders an animal susceptible (sensitive) to anaphylactic shock following a subsequent inoculum (shocking dose) of the same antigen (anaphylactogen).
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Among the factors that need to be considered are the age at which the sensitization dose(s) occurs, the time between sensitizing doses, and the route(s) of administration of the sensitizing dose.