Sensitizing dose | definition of sensitizing dose by Medical dictionary
in experimental anaphylaxis, the antigenic inoculum that renders an animal susceptible (sensitive) to anaphylactic shock following a subsequent inoculum (shocking dose) of the same antigen (anaphylactogen).
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It was anticipated that only the group of mice administered with 10 mg/kg showed a significant reduction in the mean values of skin thickness when compared with the mean values of other groups after applying a sensitizing dose
of DNCB (Table III).
Among the factors that need to be considered are the age at which the sensitization dose(s) occurs, the time between sensitizing doses
, and the route(s) of administration of the sensitizing dose