sensitization


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sensitization

 [sen″sĭ-tĭ-za´shun]
2. exposure to allergen that results in the development of hypersensitivity.
3. the coating of erythrocytes with antibody so that they are subject to lysis by complement in the presence of homologous antigen, the first stage of a complement fixation test.
autoerythrocyte sensitization see autoerythrocyte sensitization syndrome.

sen·si·ti·za·tion

(sen'si-ti-zā'shŭn),
1. Immunization, especially with reference to antigens (immunogens) not associated with infection; the induction of acquired sensitivity or of allergy.
2. In substance use/abuse parlance, the increased response seen to subsequent administration of the substance.

sensitization

Immunology The process in which a person acquires the ability to react to an antigen, usually of nonself origin. See Secondary–immune response. Cf Primary–immune response.

sen·si·ti·za·tion

(sen'si-tī-zā'shŭn)
Immunization, especially with reference to antigens (immunogens) not associated with infection; the induction of acquired sensitivity or of allergy.

sensitization

The preliminary exposure of a person to an ALLERGEN that leads to ANTIBODY production by the immune system and, on subsequent exposure, to an ALLERGIC or hypersensitivity reaction. Immunoglobulin Type E (IgE) is the main type of antibody involved.

sensitization

the state in which an enhanced IMMUNE RESPONSE is provoked by a second exposure to an ANTIGEN. This may be an allergic response (see ALLERGY).

sensitization 

1. A state or condition in which the response to a second or later stimulus (e.g. a drug) is greater than the response to the original stimulus (e.g. first administration of the drug). 2. The process in which exposure to an antigen results in the development of hypersensitivity.

sen·si·ti·za·tion

(sen'si-tī-zā'shŭn)
1. Immunization, especially with reference to antigens (immunogens) not associated with infection; induction of acquired sensitivity or of allergy.
2. In substance use/abuse parlance, increased response seen to subsequent administration of the substance.

Patient discussion about sensitization

Q. I had cataract surgery with iol implant, and ever since I have awful light sensitivity. Any ideas? I can't go into a "super store" without my sunglasses. My eyes ache at the end of the day. My doctor says "I don't know!"

A. May sound a bit silly question, but have you tried to consult your ophthalmologist (eye doctor, e.g. the one that performed the operation) about it? Cataract surgery, although considered very successful, isn't problem-free. Primary physician may not have the necessary specialization to deal with these subjects.

Q. I heard that patients are highly sensitive to their senses? what are the most common symptoms of fibromyalgia and can they be aggravated? I heard that patients are highly sensitive to their senses?

A. Great answeer...couldn't agree more!

Q. when my aunt went through chemo (for colon cancer) her palms became VERY sensitive and had a burning feeling is there any way to prevent this from happening to my mom who is starting her chemo now? If not, what it the best treatment for it?

A. What you describe sounds like peripheral neuropathy, a well known side effect of platinum chemotherapy which is used for colon cancer. Several measures, including giving infusion of calcium and magnesium, and glutathione were found to reduce the rate of this complication, although further studies are necessary.

However, the information is only general advice, since I haven't examined your mother so if you have any questions about this subject, it may be wise to consult a doctor (e.g. oncologist).

You may read more here:
http://www.nlm.nih.gov/medlineplus/cancerchemotherapy.html

More discussions about sensitization
References in periodicals archive ?
In our sample, the average class score severity was consistent with mild HDM sensitization (DP 2.3 and DF 2.2); however, this sensitization level needed clinical correlation with ADs.
They found these PSPs were primarily characterized by varying degrees of pain sensitization. The PSP with the highest degree of sensitization had the highest risk of developing persistent knee pain.
Although higher levels of total serum IgE have been associated with poorer asthma outcomes (29,30) and higher health care costs, (31) these levels are variable, affected by genetics, race, cigarette smoking, and steroid use, and are, therefore, not a reliable indicator of allergen sensitization and not a substitute for specific IgE allergen testing.
A nationwide survey of inhalant allergens sensitization and levels of indoor major allergens in Korea.
Interestingly, in the present study, we found that the testosterone-induced cross-locomotor sensitization was not long lasting.
To reach this goal, we evaluated the role of foods as triggers of urticaria exacerbation in patients with CSU using self-reported data, IgE sensitization, and challenge tests.
The allergic sensitization in infants with atopic eczema from different countries.
In 2012 Titani was exposed to unsafe level of volatile organic compounds and a melange of particulates, fumes, dust, and unidentified stuff in her workplace, and since then has researched her resulting asthma, central sensitization, and three central sensitivity syndromes--multiple chemical sensitivities, irritable larynx syndrome, and chronic fatigue syndrome--and sharing the information with others who may suffer from the same conditions.
Hamzavi described as "surprising and unusual." She called for larger studies exploring factors for the noted increase among all races, such as changes in testing methods, food avoidance, and increasing sensitization. "Understanding the changes in peanut sensitization over time is a crucial step in determining the likelihood of clinical reactivity," she said.
Allergy to pollen of date palm (6.6%) came in the sixth skin sensitization after house mite dust (17.9%), olive tree (12.4%), German cockroach (10.5%), Parietaria in (10.1%), and cypress tree (9%) and before the 5 grasses (6%).
The inclusion criteria were as follows: a diagnosis of allergic rhinitis for at least 2 years, specific symptoms of allergic rhinitis (an allergic rhinitis questionnaire), detected sensitization, the absence of nonallergic disorders of the nasopharynx and other organs and systems, age of patients from 4 years to 60 years, and distribution by sex in the ratio 1 : 1.2.
Sensitization frequencies to nickel, cobalt, and chromium were analysed according to European baseline series patch testing results.