Among the anthraquinones reported to be present in Rhubarb (Ye et al., 2007), Sennosides
A and Sennoside
B) are considered to be the purgative components (Xiao et al., 1980; Zwaving, 1972), Rhein and Physcion possess antitumor and anti-inflammatory properties (Zwaving, 1972; He et al., 2011), with the latter presenting also hepatoprotective, antifungal and anticancer activities (He et al., 2011).
On the day before colonoscopy, patients in both groups took a 5 mg mosapride citrate hydrate tablet (Gasmotin) before each meal and 24 mg sennoside
(Pursennid) at bedtime.
yields in Tinnevelly senna affected by deflowering and leaf maturity.
A+B calcium salt was used as a purgative in this study.
Stock solutions of paeoniflorin, ecdysterone, amygdalin, mulberroside A, caffeic acid, ferulic acid, salvianolic acid B, astragaloside IV, formononetin, cryptotanshinone, and tanshinone IIA were prepared separately in methanol to achieve a high concentration of 1.0mg [mL.sup.-1] and chlorogenic acid, geniposide, sennoside
B, and puerarin were prepared as internal standards (ISs) with the same way to achieve a concentration of 100 ng [mL.sup.-1].
Pundarikakshudu, "In vitro studies on guar gum based formulation for the colon targeted delivery of sennosides
,' Journal of Pharmacy and Pharmaceutical Sciences, vol.
When transport rates were monitored in the secretory (basolateral to apical) direction, comparatively higher permeability coefficients and % transport were observed (except for sennoside
A at 100 [micro]M; Table 1).
treatment does not cause habituation and secondary hyperaldosteronism in rats.
The product has 67% more sennosides
per tablet, the company notes, allowing users to reduce the number of tablets they take and lower per-dose costs.
He had tried eating a high-fiber diet and taking polyethylene glycol, docusate, and sennosides
. However, this resulted in only minimal relief of his symptoms.
[25.] Mukhopadhyay MJ, Saha A, Dutta A, De B, Mukherjee A (1998) Genotoxicity of sennosides
on the bone marrow cells of mice.
has expanded its Neemrana, India, facility, which will be dedicated exclusively to the production of Sennosides