senile plaque
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se·nile plaque
an obsolete term for neuritic plaque.
Farlex Partner Medical Dictionary © Farlex 2012
senile plaque
A histologic finding consisting of a core of extracellular amyloid with an amyloidogenic fragment (betaA4) derived from amyloid precursor protein, surrounded by a tangled spherical mass of argyrophilic cholinergic neuritis (axons/dendrites) seen in the grey matter (neocortex, hippocampus, amygdala, less commonly, basal ganglia and elsewhere) in the brains of older persons, but markedly increased in Alzheimer’s disease.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
se·nile plaque
(sen'il plak)A spheric mass composed primarily of amyloid fibrils and interwoven neuronal processes, frequently, although not exclusively, observed in Alzheimer disease.
Synonym(s): neuritic plaque.
Synonym(s): neuritic plaque.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Senile plaque
—Structures composed of parts of neurons surrounding brain proteins called beta-amyloid deposits found in the brains of people with AD.
Mentioned in: Alzheimer's Disease
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.