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A free radical resulting from the removal of one hydrogen atom with its electron during the process of dehydrogenation of a hydroquinone to quinone or similar compound (for example, flavin mononucleotide).
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Oxidation of dopamine and PEA by MAO-B can lead to the production of neurotoxic compounds such as hydrogen peroxide, semiquinones (Klegeris et al.
Oxidation of catechols to semiquinones and quinones is a mechanism of tumor initiation not only for endogenous estrogens, but also for synthetic estrogens such as hexestrol and diethylstilbestrol, a human carcinogen.
5] from six cities and found large quantities of radicals with characteristics similar to semiquinones (Dellinger et al.