We assessed the relationship of gynecomastia, metastasis, and disease prognosis within subgroups according to
seminomatous and nonseminomatous histology.
Treatment outcome and patterns of relapse following adjuvant carboplatin for stage I testicular
seminomatous germ-cell tumour: Results from a 17-year U.K.
Free beta-subunit of human chorionic gonadotropin in serum is a diagnostically sensitive marker of
seminomatous testicular cancer.
Recommendations are for its use alongside AFP however it can also be useful for
seminomatous tumours where AFP is not (3).
Alpha-Fetoprotein is also recommended for differential diagnosis of nonseminomatous and
seminomatous germ cell tumors.
Seminomatous types are more sensitive to radiation, while the nonseminomatous types are more sensitive to chemotherapy.
The patient underwent radical orchiectomy that revealed a pure
seminomatous tumor of the left testicle measuring 7.5 cm in its maximum dimension.
Histologically they comprise
seminomatous and/or teratomatous elements.
(2) Like gonadal neoplasms, extragonadal germ-cell tumors are classified as either
seminomatous or nonseminomatous.
The most common malignant neoplasms of the testis are
seminomatous germ cell tumors (GCTs) and nonseminomatous germ cell tumors (NSGCTs) occurring in postpubertal men, and germ cell neoplasia in situ (GCNIS) is the precursor lesion to both entities.
The distinction of
seminomatous from nonseminomatous GCTs is critical for management and predicting prognostic outcomes.
Hematologic disorders associated with primary mediastinalnon-
seminomatous germ cell tumors.