seminiferous tubule dysgenesis


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Related to seminiferous tubule dysgenesis: Klinefelter syndrome

sem·i·nif·er·ous tu·bule dys·gen·e·sis

rarely used term for a disorder in which the seminiferous tubules exhibit an abnormal cytoarchitecture and extensive hyalinization; the testes are small, and few spermatozoa are formed; the body habitus may be eunuchoid, and gynecomastia may be present; urinary gonadotropin output is usually high, and the incidence of mental deficiency and illness increased; sex chromatin may be male or female, and androgen secretion ranges from subnormal to normal. It is a constant feature of (and the term may be used synonymously with) Klinefelter syndrome.
Synonym(s): germinal aplasia

Klinefelter syndrome

A syndrome with a 47, XXY chromosome complement, in which the subjects are phenotypically male but have seminiferous tubule dysgenesis, elevated plasma and urinary gonadotropins, variable gynecomastia, eunuchoid habitus and possibly female secondary sex characteristics. Some patients are chromosomal mosaics, with two or more cell lines of different chromosome constitution.

sem·i·nif·er·ous tu·bule dys·gen·e·sis

(sem'i-nif'ĕr-ŭs tū'byūl dis-jen'ĕ-sis)
A disorder in which the seminiferous tubules exhibit an abnormal cytoarchitecture and extensive hyalinization; the testes are small, and few sperms are formed; the body habitus may be eunuchoid, and gynecomastia may be present; urinary gonadotropin output is usually high, and the incidence of mental deficiency and illness increased; sex chromatin may be male or female, and androgen secretion ranges from subnormal to normal. It is a constant feature of (and is often used synonymously with) Klinefelter syndrome

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