Ameliorative effects of curcumin on the structural parameters of seminiferous tubules
and Leydig cells in metronidazole-treated mice: a stereological approach.
Testis of rat from group 1 showing the normal histological structure of seminiferous tubules
, normal spermatogenesis (stage VIII tubule).
(A) Seminiferous tubules
of control group with normal conjoined germinative epithelial cells and spermatozoa in the lumen.
The data indicated the significantly higher percentage of seminiferous tubules
containing MNGCs in the AA-treated group than in the AA+L-cys-treated group (p<0.001), as shown in Table 3.
The results of the microscopic examination showed no clear difference between the densities of spermatogonia type A, primary spermatocytes at the pachytene stage, spermatids at the zygotene stage and spermatozoa in the seminiferous tubules
of vaccinated (Figure 2Ba) and control lambs (Figure 2Bb) at week 30 after the primary immunization.
The low expression rate of CDC25A in infertile men is the result of the reduction of spermatogenic cycles in the seminiferous tubules
and shows that the CDC25 phosphatase contributes to the hyperphosphorylation of M-phase promoting factor (MPF) and CDC25 that are important to complete the meiosis (24).
The positive cells in the tubular compartments were distributed in the spermatogenic cells and Sertoli cells of the seminiferous tubules
In contrast to primates, for example, marmosets, two or more cellular associations (stages of seminiferous epithelium) were identified from a cross section of the seminiferous tubule
, because spermatogenesis as in marmoset is asymmetrically distributed, resulting in more than one stage per cross section of seminiferous tubule
During the current investigation, the histological examination of testis showed no statistically significant difference in the mean diameters of the seminiferous tubules
among various groups.
 also studied the germ cells but did not study the seminiferous tubule
We used a rat seminiferous tubule
culture model mimicking the in vivo situation in the pubertal rat (Staub et al., 2000).
In mammalian testis Spermatogenesis takes place in the seminiferous tubules
which are composed of Sertoli cells (SCs) and maturing germ cells surrounded by one (rodents) or more (large animals) layer(s) of peritubular myoid cells [8,9].