semaphorin


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semaphorin

(sem-a-fōr'in),
A family of membrane proteins including S-I, S-II, S-III, S-III/D and collapsing 1 that guide growth cones of axons by selective repulsion.
Farlex Partner Medical Dictionary © Farlex 2012
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Semaphorin signaling appears to shape the physical architecture of the brain and influence circuitry governing body weight.
Scientists discover molecules that are wired for obesity
Semaphorin 3C is involved in the progression of gastric cancer.
Importance of the putative furin recognition site [sub.742][RNRR.sub.745] for antiangiogenic Sema3C activity in vitro
Signaling by semaphorin receptors: cell guidance and beyond.
Semaphorin3A: A potential therapeutic tool in immune-mediated diseases
Tanaka, "Semaphorin 3E secreted by damaged hepatocytes regulates the sinusoidal regeneration and liver fibrosis during liver regeneration," The American Journal of Pathology, vol.
Transcriptome Analysis of Porcine PBMCs Reveals the Immune Cascade Response and Gene Ontology Terms Related to Cell Death and Fibrosis in the Progression of Liver Failure
Moreover, besides its role as receptor for class 3 semaphorins, NRP1 is also considered a coreceptor for some growth factors, such as VEGF or PDGF.
Neuropilin 1 Mediates Keratinocyte Growth Factor Signaling in Adipose-Derived Stem Cells: Potential Involvement in Adipogenesis
Currently, a number of evidences indicated that neural guidance cues and their binding sites, such as ephrin, Netrin, and semaphorins, function as angiogenic regulators.
Netrin as a Novel Biomarker and Its Therapeutic Implications in Diabetes Mellitus and Diabetes-Associated Complications
Goodman, "The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules," Cell, vol.
Circulating Semaphorin 4D as a Marker for Predicting Radiographic Progression in Patients with Rheumatoid Arthritis
Tessier-Lavigne," Neuropilin is a receptor for the axonal chemorepellent Semaphorin III," Cell, vol.
Hippocampal pathophysiology: commonality shared by temporal lobe epilepsy and psychiatric disorders
Hoyland, "Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc," Arthritis Research & Therapy, vol.
Semaphorin 3A Inhibits Inflammation in Chondrocytes under Excessive Mechanical Stress
Besides VEGF, TAMs release a panel of proangiogenic factors which include TNF-[alpha], basic fibroblast growth factor (bFGF), CXCL8/IL-8, thymidine phosphorylase (TP), adrenomedullin (ADM), and semaphorin 4D (Sema4D) [88-91] (Figure 2).
Macrophage Polarization in Chronic Inflammatory Diseases: Killers or Builders?
(2000) Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling.
Negative regulation of B cell responses and self-tolerance to RNA-related lupus self-antigen
SEMA3A encodes for semaphorin 3A, a protein that interacts with neuropilins.
Update on the Genetics of Idiopathic Hypogonadotropic Hypogonadism

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