selegiline


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selegiline

 [sĕ-lej´ĭ-lēn]
an agent used in treatment of parkinsonism; used as the hydrochloride salt in conjunction with levodopa and carbidopa.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

selegiline

(sə-lĕj′ə-lēn′)
n.
A selective monoamine oxidase inhibitor, C13H17N, used transdermally as an antidepressant and in its hydrochloride form in conjunction with levodopa and carbidopa to treat patients with Parkinson's disease.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

deprenyl

Alternative pharmacology
A prescription drug used to treat Parkinson’s disease, which has acquired currency among some practitioners of alternative medicine as an anti-ageing substance; deprenyl acts on the substantia nigra., a region of the brain that is believed to age more rapidly than others, by blocking the degradation of dopaminergic neurotransmitters.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

selegiline

l-Deprenyl Neuropharmacology A selective monoamine oxidase type B inhibitor which, with l-dopa, may be useful for early symptomatic treatment of parkinsonism
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

selegiline

A selective MONOAMINE OXIDASE INHIBITOR drug used in the treatment of PARKINSONISM. Selegiline is thought to retard the breakdown of DOPAMINE. Brand names are Eldepryl and Vivapril.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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Like selegiline, it has effects on dopamine levels.
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Neuroprotective Effect of Ceftriaxone and Selegiline on Scopolamine Induced Cognitive Impairment in Mice.
Evaluation of the Effect of Ceftriaxone on Lipid Peroxidation and Antioxidant Levels in Mice
* The MAO-B inhibitors selegiline and rasagiline may also be considered for initial therapy but are more commonly used as adjunct therapy.
Parkinson's disease: A treatment guide: By following this stepwise approach, you can confidently incorporate newer agents into your armamentarium with little or no consultation with subspecialists
In each study, the randomized patient population was divided into 3 subgroups based on the use of concomitant medications at study entry: a dopaminergic agonist group, a MAO-B inhibitor group (rasagiline and selegiline), and an amantadine group.
Dosing Patterns during Conversion to IPX066, Extended-Release Carbidopa-Levodopa (ER CD-LD), in Parkinson's Disease with Motor Fluctuations
(a) Selegiline (0.038 [micro]M); (b) 4a (0.42 [micro]M); (c) 4b (0.36 [micro]M); (d) 4c (0.69 [micro]M).
Synthesis and Evaluation of N-[1-(((3,4-Diphenylthiazol-2(3H)-ylidene)amino)methyl)cyclopentyl]acetamide Derivatives for the Treatment of Diseases Belonging to MAOs
Levodopa, dopamine agonists (apomorphine, bromocriptine, cabergoline), monoamine oxidase B inhibitors (selegiline, amantadine), anticholinergics (biperiden, bornaprine), peripheral dopamine blockers (domperidone) and catecholamine methyltransferase inhibitors are used in the medical treatment of the disease to maintain the balance between the cholinergic and dopaminergic activity (5).
An Experience of General Anesthesia in a Case of Parkinson's Disease/Parkinson Hastaligi Olan Olguda Genel Anestezi Deneyimi
Standards of moclobemide and selegiline are used as positive controls for MAO-A and MAO-B inhibition, respectively.
Hypericum perforatum: Synthesis of Active Principles during Flowering and Fruitification--Novel Aspects of Biological Potential
Recently, our research group has demonstrated the prospective of drug loaded nanospheres embedded films in enhancing the bioavailability of selegiline when delivered through buccal route (9).
Mucoadhesive Buccal Films Embedded with Antiviral Drug Loaded Nanospheres/Antiviral Etken Madde Yuklu Nanokurelerin Yerlestirildigi Mukoadhezif Bukkal Fimler
But then they jump to suggestions that have not yet been proven, including supplementation with "huge doses of vitamin D" and melatonin, plus metformin (a diabetes drug) and selegiline (a drug used to treat early Parkinson's and depression).
Aging examined from a different lens
Legal medication that could result in drug-driving charge | |Amphetamines (eg Dexamphetamine or Selegiline) | Clonazepam | | |Diazepam | | Flunitrazepam | | Lorazepam | | | Morphine or opiate and opioidbased drugs (eg codeine, tramadol or fentanyl) | |Oxazepam | | Temazepam
Drug-driving arrests jump 140%; ALERT OVER MEDICATIONS - INCLUDING HAY FEVER CURES - WHICH COULD LEAD TO DRIVING BANS
Considering that this patient mainly suffered from the extrapyramidal symptom, she was prescribed levodopa 450 mg/d and selegiline 10 mg/d.
Idiopathic Basal Ganglia Calcification Presented with Progressive Supranuclear Palsy-like Features
Dopaminergic medications, such as selegiline or pramipexole, are used for early-stage Parkinsons disease (PD), and also to slow the progression of symptoms in dementia.
Modafinil: Can this "smart drug" help a flagging memory? The prescription drug enhances memory, learning, and more

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