selegiline


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selegiline

 [sĕ-lej´ĭ-lēn]
an agent used in treatment of parkinsonism; used as the hydrochloride salt in conjunction with levodopa and carbidopa.

selegiline

(sə-lĕj′ə-lēn′)
n.
A selective monoamine oxidase inhibitor, C13H17N, used transdermally as an antidepressant and in its hydrochloride form in conjunction with levodopa and carbidopa to treat patients with Parkinson's disease.

deprenyl

Alternative pharmacology
A prescription drug used to treat Parkinson’s disease, which has acquired currency among some practitioners of alternative medicine as an anti-ageing substance; deprenyl acts on the substantia nigra., a region of the brain that is believed to age more rapidly than others, by blocking the degradation of dopaminergic neurotransmitters.

selegiline

l-Deprenyl Neuropharmacology A selective monoamine oxidase type B inhibitor which, with l-dopa, may be useful for early symptomatic treatment of parkinsonism

selegiline

A selective MONOAMINE OXIDASE INHIBITOR drug used in the treatment of PARKINSONISM. Selegiline is thought to retard the breakdown of DOPAMINE. Brand names are Eldepryl and Vivapril.
References in periodicals archive ?
Neuroprotective Effect of Ceftriaxone and Selegiline on Scopolamine Induced Cognitive Impairment in Mice.
* The MAO-B inhibitors selegiline and rasagiline may also be considered for initial therapy but are more commonly used as adjunct therapy.
In each study, the randomized patient population was divided into 3 subgroups based on the use of concomitant medications at study entry: a dopaminergic agonist group, a MAO-B inhibitor group (rasagiline and selegiline), and an amantadine group.
Levodopa, dopamine agonists (apomorphine, bromocriptine, cabergoline), monoamine oxidase B inhibitors (selegiline, amantadine), anticholinergics (biperiden, bornaprine), peripheral dopamine blockers (domperidone) and catecholamine methyltransferase inhibitors are used in the medical treatment of the disease to maintain the balance between the cholinergic and dopaminergic activity (5).
Standards of moclobemide and selegiline are used as positive controls for MAO-A and MAO-B inhibition, respectively.
Recently, our research group has demonstrated the prospective of drug loaded nanospheres embedded films in enhancing the bioavailability of selegiline when delivered through buccal route (9).
But then they jump to suggestions that have not yet been proven, including supplementation with "huge doses of vitamin D" and melatonin, plus metformin (a diabetes drug) and selegiline (a drug used to treat early Parkinson's and depression).
Legal medication that could result in drug-driving charge | |Amphetamines (eg Dexamphetamine or Selegiline) | Clonazepam | | |Diazepam | | Flunitrazepam | | Lorazepam | | | Morphine or opiate and opioidbased drugs (eg codeine, tramadol or fentanyl) | |Oxazepam | | Temazepam
Considering that this patient mainly suffered from the extrapyramidal symptom, she was prescribed levodopa 450 mg/d and selegiline 10 mg/d.
Dopaminergic medications, such as selegiline or pramipexole, are used for early-stage Parkinsons disease (PD), and also to slow the progression of symptoms in dementia.