selective serotonin re-uptake inhibitors

selective serotonin re-uptake inhibitors (SSRIs)

A range of drugs that act at the clefts of synapses in the brain preventing released SEROTONIN from being removed and thus increasing its action as a NEUROTRANSMITTER. These drugs are used to treat depression, anxiety, panic disorders, agoraphobia, bulimia, obsessive-compulsive disorders and post-traumatic stress disorder syndrome. Generic names are CITALOPRAM, FLUOXETINE, FLUVOXAMINE, PAROXETINE, and SERTRALINE. Other drugs (e.g. VENLAFAXINE) are specific promoters of the action of both serotonin and noradrenaline and are termed selective noradrenaline and serotonin inhibitors (SNRIs). Doubts have been expressed as to the specificity of some of the drugs in this group for treating certain of these conditions. Brand names can be found in the generic entries.
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