selective plane illumination microscopy


Also found in: Acronyms.

selective plane illumination microscopy

a fast, optically stable modification of confocal microscopy in which, instead of using a single point light source that is scanned over the specimen, a single plane of light source is used. This process provides faster image acquisition and clear three-dimensional reconstruction of objects larger than those usable for confocal microscopy.
References in periodicals archive ?
Basic selective plane illumination microscopy (SPIM) (as introduced in this review thus far) is capable of acquiring high-speed movies in a single plane of the sample.
Multidirectional selective plane illumination microscopy (mSPIM) (Huisken and Stainier.
Imaging multicellular specimens with real-time optimized tiling light-sheet selective plane illumination microscopy. Nat.
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