selective norepinephrine reuptake inhibitor

selective norepinephrine reuptake inhibitor

a class of chemical compounds that selectively, to varying degrees, inhibit the reuptake of norepinephrine by the presynaptic neurons and are posited to exert their antidepressant effect by this mechanism.

se·lec·tive nor·ep·i·neph·rine re·up·take in·hib·i·tor

(SNRI) (sĕ-lektiv nōr-epi-nefrin rē-ŭptāk in-hibi-tŏr)
A class of chemical compounds that selectively, to varying degrees, inhibit reuptake of norepinephrine by the presynaptic neurons; thought to exert their antidepressant effect by this mechanism.

se·lec·tive nor·ep·i·neph·rine re·up·take in·hib·i·tor

(sĕ-lektiv nōr-epi-nefrin rē-ŭptāk in-hibi-tŏr)
Class of chemical compounds that selectively, to varying degrees, inhibit reuptake of norepinephrine.
References in periodicals archive ?
Strattera, a selective norepinephrine reuptake inhibitor, is approved for both pediatric and adult patients.
SPN-812 is a selective norepinephrine reuptake inhibitor that the company believes could be more effective and with an improved side effect profile compared to other non-stimulant treatments for ADHD due to its different pharmacological profile.
This study used a selective norepinephrine reuptake inhibitor, nisoxetine, to focus on the diet-induced alterations in feeding that emerge with onset of weight gain.
Stimulants such as methylphenidate, amphetamines, and pemoline, as well as the selective norepinephrine reuptake inhibitor atomoxetine, are known to raise heart rate and to increase systolic blood pressure by approximately 2-5 mm Hg and diastolic blood pressure by 1-3 mm Hg.
Between 5% and 14% of patients on a selective serotonin reuptake inhibitor (SSRI) or a selective norepinephrine reuptake inhibitor (SNRI) develop drug-induced excessive sweating.
Reboxetine is a selective norepinephrine reuptake inhibitor used in the United Kingdom.
It is a selective norepinephrine reuptake inhibitor. Although the exact mechanism is unknown, scientists speculate that it works by blocking or slowing the reuptake of norepinephrine, which regulates attention, impulsivity, and activity levels in the brain.
Major finding: Patients with depression who did not respond adequately to a course of selective serotonin reuptake inhibitor or selective norepinephrine reuptake inhibitor therapy and who were then switched to double-blind treatment with the novel antidepressant vortioxetine had a 55% remission rate after 8 weeks of therapy.
A selective norepinephrine reuptake inhibitor, atomoxetine relieves symptoms for as long as 12 hours and does not exacerbate comorbid tics or mood disorders.
Physicians and patients may be alarmed by recent changes to the product labels of the selective serotonin reuptake inhibitors and the selective norepinephrine reuptake inhibitor venlafaxine with respect to their use during pregnancy.
Stimulants such as methylphenvdate, amphetamines, and pemoline, as well as the selective norepinephrine reuptake inhibitor atomoxetine, are known to raise heart rate and to increase systolic blood pressure by approximately 2-5 mm Hg and diastolic blood pressure by 1-3 mm Hg.
Tomoxetine, a selective norepinephrine reuptake inhibitor, has been shown to be effective for adult ADHD in double-blind crossover studies.

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