selectin


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se·lec·tin

(sĕ-lek'tin),
A cell surface molecule involved in immune adhesion and cell trafficking.
[L. se-ligo, pp. se-lectum, to sort, choose, + -in]

se·lec·tin

(sĕ-lek'tin)
A cell surface molecule involved in immune adhesion and cell trafficking.
[L. se-ligo, pp. se-lectum, to sort, choose, + -in]

selectin

Any of a group of cell surface molecules that influence the attachment and movement of white blood cells to other cells and to the lining of blood vessels, e.g., in inflammatory diseases and conditions.

P-selectins

An adhesion receptor molecule for white blood cells that functions during inflammation and tissue repair. Binding with P-selectin glycoprotein ligand 1, it controls the flow of white blood cells and their adhesion to blood vessel walls. It is viewed as a key factor in thrombosis.

selectin

one of a group of cell adhesion membrane GLYCOPROTEIN molecules that binds to carbohydrates via a LECTIN-like DOMAIN. Selectins mediate the binding of LEUKOCYTES to the vascular ENDOTHELIUM. Three selectins have been identified E-, L-and P- selectin.
References in periodicals archive ?
Actin, Selectin, and the Energid logo are trademarks of Energid Technologies Corporation.
Crow said she wants the community to be closely involved in the selectin of the design and final memorial.
3) The most important initiators of adhesion are the three selectins expressed on leukocytes (L-selectin), endothelial cells (E-selectin), and activated platelets (P-selectin).
Selectin family of adhesion molecules such as E-, L- and P-selectin move to the endothelial surface for tethering and rolling of leukocytes on to the vascular wall (Balciunas et al.
Selectins and selectin ligands in extravasation of cancer cells and organ selectivity of metastasis.
SELECTIN EXPRESSION NOT DETECTED IN HUMAN PAPILLOMAVIRUS POSITIVE AND NEGATIVE CERVICAL CELL LINES.
E-selectin belongs to a family of structurally related selectin molecule; selectins E, P and L participate in endothelial leukocyte adhesion (1).
Specifically, after systemic immunization the predominant homing receptor on antibody secreting cells is the L selectin, after oral immunization the ad4bd7 integrin, and after nasal immunization a large portion expressed both the L selectin and the ad4bd7 integrin.
In vivo, selectin binding is highly specific with rapid dynamics, allowing fast-flowing leukocytes to bind and roll on the endothelium.
Weekly biomarkers of inflammation included plasma interleukin-6, tumor necrosis factor-a soluble receptor II (sTNF-RII), soluble platelet selectin (sP-selectin), and C-reactive protein (CRP).
sE selectin had a significant decrease after 4 hours in total and in the pomegranate juice group, followed by a significant decrease after 1 month in both groups.
They are also working to design compounds to inactivate a selectin called ELAM-1 that sometimes gets overzealous in summoning white blood cells to injured tissues.