selected ion monitoring


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selected ion monitoring

A term defined in the context of mass spectrometry as the practice of monitoring and recording ion currents at one or more selected ion m/z values with time, rather than recording full mass spectra, as sample is introduced into the ion source. Because the detector is integrating signal for a longer time at the relevant ion, limits of detection can be lowered, at a cost of increased susceptibility of the analysis to unexpected interferences.
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Simple selected ion monitoring capillary gas chromatographic-mass spectrometric method for the determination of cotinine in serum, urine and oral samples.
Assay of stable isotope labeled urea in biological fluids by selected ion monitoring.
The structures of the compounds eluting from the HPLC were then confirmed using HPLC-MSM5, and the quantity of the MPA contaminating the MPAG sample was determined using HPLC-MS with selected ion monitoring (SI1VI), as described previously (8).
Detection was by massspectrum detector (1100 MSD; Hewlett-Packard) using selected ion monitoring in atmospheric pressure chemical ionization mode with positive polarity.

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