segregation

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segregation

 [seg″rĕ-ga´shun]
the separation of allelic genes during meiosis as homologous chromosomes begin to migrate toward opposite poles of the cell, so that eventually the members of each pair of allelic genes go to separate gametes.

seg·re·ga·tion

(seg'rĕ-gā'shŭn),
1. Removal of certain parts from a mass, for example, those with infectious diseases.
2. Separation of contrasting characters in the offspring of heterozygotes.
3. Separation of the paired state of genes, which occurs at the reduction division of meiosis; only one member of each somatic gene pair is normally included in each sperm or oocyte; for example, an individual heterozygous for a gene pair, Aa, will form gametes half containing gene A and half containing gene a.
4. Progressive restriction of potencies in the zygote to the following embryo.
[L. segrego, pp. -atus, to set apart from the flock, separate]

segregation

(sĕg′rĭ-gā′shən)
n.
1. The act or process of segregating or the condition of being segregated.
2. Genetics The separation of paired alleles or homologous chromosomes, especially during meiosis, so that the members of each pair appear in different gametes.

seg·re·ga·tion

(seg'rĕ-gā'shŭn)
1. Removal of certain parts from a mass (e.g., those with infectious diseases).
2. Separation of contrasting characters in the offspring of heterozygotes.
3. Separation of the paired state of genes, which occurs at the reduction division of meiosis; only one member of each somatic gene pair is normally included in each sperm or ovum.
4. Progressive restriction of potencies in the zygote to the following embryo.
[L. segrego, pp. -atus, to set apart from the flock, separate]

segregation

  1. the separation of HOMOLOGOUS CHROMOSOMES during anaphase 1 of MEIOSIS, to produce gametes containing only one allele of each gene. Such an occurrence is the physical mechanism underlying the first law of MENDELIAN GENETICS and is particularly important when the two separated alleles are different.
  2. an ability of bacterial REPLICONS to be partitioned accurately and evenly between daughter cells during CELL DIVISION. See par LOCUS.
References in periodicals archive ?
She says two of her clients were held in segregation. Antonio Comacho Negron, imprisoned at the Federal Correctional Institution in Allenwood, Pennsylvania, was held in a Secure Housing Unit from September 11 until October 2.
As of October 31, Williams had not been released from administrative segregation, according to Boyle.
The patterns of chromosome segregation in eggs from triploids, following inhibition of PB1, were similar to those in diploid eggs following the same treatment, which implies that similar mechanisms underlie the segregation of chromosomes during meiosis II.
Some companies mentioned specific accounting areas affected by the segregation of duties material weaknesses.
Some companies discussed compensating controls that may partially mitigate the segregation of duties problem.
Several entities and commentators offer guidance and suggestions for addressing segregation of duties challenges, especially for small companies.
One obvious solution to segregation of duties weaknesses is to add more people to the organization.
In contrast, a common theme among many commentators appears to be that hiring more employees may not be the best solution to segregation of duties material weaknesses.
EXHIBIT 1 Sample of Smaller Companies with Material Weaknesses Related to Segregation of Duties (116 Companies) Company Size* Median Market Value $4,923,425 Revenues $ 81,150 Assets $1,066,443 Net Income -$1,274,507 SIC Codes Companies 0000-1999 Agriculture, Mining, and Construction 18 2000-3999 Manufacturing 33 4000-4999 Transportation and Communication 8 5000-5999 Wholesale and Retail 8 6000-6999 Financial, Insurance, and Real Estate 8 7000-8999 Services 36 9995 Nonoperating 5 Total 116 Total Number of Material Weaknesses Median number of material weaknesses per company 2 Range of material weaknesses per company 1-8 * Not all companies reported figures in this section; 42 companies reported revenues of 0.