sedoheptulose


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se·do·hep·tu·lose

(sē'dō-hep'tyū-lōs),
A 2-ketoheptulose formed metabolically in the pentose monophosphate pathway as the 7-phosphate by condensation of d-xylulose 5-phosphate and d-ribose 5-phosphate, splitting out d-glyceraldehyde 3-phosphate; the unphosphorylated sugar is found naturally in Sedum (stonecrop).
Synonym(s): d-altro-2-heptulose
Farlex Partner Medical Dictionary © Farlex 2012
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In addition to compounds related to the glycolytic pathway (dihydroxyacetone phosphate [DHAP], F-1,6-dP, lactic acid) and purine metabolism (AMP, ATP, GMP, hypoxanthine, IP, etc.), other compounds, including 6-phosphogluconic acid (6PG), sedoheptulose 7-phosphate (S7P), citric acid, fumaric acid, and NAD+, showed changes in their contents in the postmortem period.
Metabolomic approach to key metabolites characterizing postmortem aged loin muscle of Japanese Black (Wagyu) cattle
Specifically, they found that the organism was missing a transaldolase and thus they allowed accumulation of sedoheptulose 7-phosphate.
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Gille et al., "The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism," Cell Metabolism, vol.
HIF1[alpha]-Induced Glycolysis Metabolism Is Essential to the Activation of Inflammatory Macrophages

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