secretoglobin


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secretoglobin

Any of a family of small secreted mammalian proteins (consisting of approx. 70 linked amino acids) of unknown function. They are highly genetically conserved. Many are potent allergens.
References in periodicals archive ?
Aprile Pilon has assumed responsibility for leading and advancing the Company's secretoglobin platform in the role of Executive Vice President and Chief Scientific Officer.
Pilon's contributions to our understanding of the field of secretoglobin biology and pharmacology are unparalleled and I am fortunate to have the opportunity to work with and learn from her", said Dr.
Pilon, the Company's Founder, has had a career-long focus on the advancement of secretoglobin protein biology and pharmacology, and the development of secretoglobin therapeutic candidates.
showed that a panel of 6 genes was superior to EpCAM and secretoglobin, family 2A, member 2 (SCGB2A2, also known as mammaglobin and hMAM) for the detection of CTCs in breast cancer, and that theses genes may serve as potential markers for CTC derived from endometrial, cervical, and ovarian cancers as well (40).
3] Human genes: KRT19, keratin 19; SCGB2A2, secretoglobin, family 2A, member 2, also known as mammaglobin; ERBB2, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian); MAGEA1, melanoma antigen family A, 1 (directs expression of antigen MZ2-E); TWIST-1, twist homolog 1 (Drosophila).
5] Human genes: ERBB2, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (also known as HER2); KRT19, keratin 19 (also known as CK19); SCGB2A2, secretoglobin, family 2A, member 2 (also known as MGB1, mammaglobin A); EPCAM, epithelial cell adhesion molecule; MUC1, mucin 1, cell surface associated; TWIST1, twist homolog 1 (Drosophila); MAGEA3, melanoma antigen family A, 3; HMBS, hydroxymethylbilane synthase (also known as PBGD).
Proceeds to Fund Continued Development of Lead Biologic Candidate, CG100, as well as the Company's Broader Recombinant Secretoglobin Platform
The last year has been important for Therabron as we are now moving toward the end of patient enrollment in the phase 2 clinical trial for CG100 and have advanced our scientific understanding of the broad potential of our recombinant human secretoglobin platform across several respiratory disorders," said Dr.
The family of CC10 proteins, also known as secretoglobins, has the potential to change the course of acute and chronic respiratory diseases, representing large markets into which few truly novel drugs have been introduced.
EU Patent Allowance Adds to Company's Growing Exclusivity Portfolio for Recombinant Secretoglobin Platform
We continue to pursue a robust intellectual property strategy and this patent allowance provides additional protections for our Recombinant Secretoglobin Platform program, which is currently supported by a growing list of potential regulatory and patent related exclusivities," said Dr.
The crystal structure of the major eat allergen Fel d 1, a member of the secretoglobin family.