secondary malignancy

metastatic cancer

Cancer which has spread in a non-contiguous fashion—by the blood, haematogenously; by the lymphatic, trans-coelomically—from a primary site of origin to a distant site.

secondary malignancy

Oncology A cancer that arises in the background of another malignancy treated by RT or chemotherapy; SM is also defined as one caused by environmental toxins, physical agents, radiation Examples ANLL–eg, AML, acute promyelocytic leukemia, acute monocytic leukemia, erythroleukemia and myelodysplastic disorders–preleukemia Leukemogenic chemotherapeutics Chlorambucil, melphalan and, combined, doxorubicin, cisplatin Physical agents causing SM–Radiation–solar, X-rays to head & neck causes 2º BCCs; latency period to 2º neoplasm 3-65 yrs Chronic irritation–Marjolin's ulcer causing skin cancer or chronic injury–eg, heat-induced SCC Scar malignancy–eg, malignant fibrous histiocytoma arising in sites with metal objects or shrapnel or malignancy induced by mechanical trauma, a relation which in humans is anecdotal, ischemia and SCC near varicose veins. See Occult primary.

Patient discussion about secondary malignancy

Q. I have met my close friend after 3 years. She is showing some signs of high depression. How can I help her? I have met my very close friend after 3 years and she is very depressed. I am worried that she is showing some signs of high depression. She talks all rubbish and negatives these days which is filled with that nonsense hopelessness. She was fine and going good when I left her and now she is completely negative in her behavior and also very depressed. She is not able to enjoy my company. She had lost her weight and her eyes reflect the bluntness. She keeps silent most of the time. How can I help her?

A. I think first you must talk to her and find out about when and how this started. Take her to all the places where you both used to go. She might have come across difficult phase in these years which would have made her depressed and she may need a support to bring her back to normal way of living. We cannot say that this is a depression which would get cured by just talking and knowing the reasons but you must help her to fight back for the thing she had lost. If there is no desired result, then do consult a physician.
http://www.youtube.com/watch?v=P9QxddJOQY4&eurl=http://www.imedix.com/health_community/vP9QxddJOQY4_nervous_system_depression_psyche?q=depression&feature=player_embedded

Q. Does staging in breast cancer is linked to metastasis and what is the use of staging?

A. stages in cancer tell of it's progress. is it benign, does it have a capsule, did it metastasized and all that. but if you are looking for more accurate and more information on that in general:
http://www.breastcancer.org/symptoms/diagnosis/staging.jsp

this should do it!

Q. What is the best pathophysiology of colorectal cancer. The pathophysiology just has to be brief and concise. It also has to include nursing considerations for the patient.

A. i'm not sure i understand your question...do you mean what is the best treatment for colorectal cancer? patophysiology is the changes the tissue acquired. if you'll give me more details on what you are looking for i'll be more then happy to help you.

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References in periodicals archive ?
In the event that a secondary malignancy occurs, contact Kite at 1-844-454-KITE (5483) to obtain instructions on patient samples to collect for testing.
Event-free survival is defined as the time from the start of Sprycel to lack of complete response at the end of the third high-risk block, relapse, secondary malignancy or death from any cause.
The most common secondary malignancy involving the urinary bladder is colorectal adenocarcinoma (Figure 8a).
Moreover, PCNSL may also present as a secondary malignancy. In addition to age and performance status, which are well known prognostic factors, symptoms, tumour volume, presence of meningeal dissemination and serum LDH level also significantly influence survival in these patients.1 Chemo-radiation therapy has remained the mainstay of management in patients with PCNSL and is associated with reasonable efficacy but with high incidence of neurotoxicity.
The primary or secondary malignancy in females with postmenopausal bleeding (PMB) is around 10%.
Secondary Malignancy. For at least 35 years after treatment, patients who have received chemotherapy or radiation are at higher risk of developing a secondary malignancy over the general population who has not been exposed to these agents [47].
Objectives of evaluation in patients with adrenal incidentaloma are (i) to rule out functioning adrenal mass and (ii) to differentiate primary from secondary malignancy. Distinguishing the masses helps in pre-operative preparation and perioperative management according to the type of functioning lesion.
Until now, there has not been a relevant large study of Chinese MM patients available to study SPMs, and no secondary malignancy after bortezomib treatment alone has been reported.
Several retrospective studies have suggested that CLL patients carry a threefold risk of developing a secondary malignancy [10].
Objective: Secondary malignancy is a major life-threatening complication facing patients afflicted with acquired immunodeficiency syndrome (AIDS).
The subjects received chemotherapy within three months of diagnosis and had no secondary malignancy within a year.
* Monitor patients at every visit for late-onset treatment effects that can produce pain, just as they are monitored for recurrent disease and secondary malignancy. Some cancer survivors may not recognize that their current pain is related to past disease or its treatments, or may consider it an untreatable complication that they have to endure.

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