secondary hyperparathyroidism


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Related to secondary hyperparathyroidism: renal secondary hyperparathyroidism

sec·on·dar·y hy·per·par·a·thy·roid·ism

hyperparathyroidism that arises as a result of disordered metabolism producing hypocalcemia, as in chronic uremia due to renal disease, malabsorption, rickets, or osteomalacia; associated with hyperplasia of the parathyroid glands.

secondary hyperparathyroidism

Endocrinology ↑ Parathyroid activity with overproduction of PTH due to parathyroid hyperplasia in response to an extraparathyroid defect that results in ↓ Ca2+ Etiology Rickets, vitamin D deficiency, chronic renal failure Organs affected Bone, GI tract, kidneys, CNS, muscle

secondary hyperparathyroidism

Excessive levels of parathyroid hormone (PTH) released in response to a low serum calcium, or a high serum phosphate level. It may be due to vitamin D deficiency or chronic kidney disease.

sec·on·dar·y hy·per·par·a·thy·roid·ism

(sekŏn-dar-ē hīpĕr-pară-thīroyd-izm)
Disorder that occurs as a complication of renal disease that affects all four parathyroid glands.
References in periodicals archive ?
Tominaga, "Current status of parathyroidectomy for secondary hyperparathyroidism in Japan," NDT Plus, vol.
Availability to take oral Lack of calcium metabolism supplements, if needed documentation Normal preoperative renal Lost to follow-up function * Causes of secondary hyperparathyroidism according to Fraser [22]: (i) steroid therapy; (ii) patients overclothing; (iii) bisphosphonate therapy; (iv) osteolytic lesions; (v) diuretic therapy; (vi) previous acute pancreatitis; (vii) state of sepsis; (viii) chronic kidney disease and hypercalciuria; (ix) intake of drugs that interact with vitamin D (e.g., phenobarbital and phenytoin); and (x) use of antacids containing aluminum that interfere with phosphate absorption.
Parathyroidectomy was performed for better control of the secondary hyperparathyroidism but the surgery was performed after the metastatic pulmonary calcifications had resolved.
* The report provides a snapshot of the global therapeutic landscape of Secondary Hyperparathyroidism
In the last decade, one of the most relevant therapeutic innovations in the field of CKD has been the introduction of paricalcitol (19-nor-1,25-dihydroxy vitamin [D.sub.2]), a selective activator of the vitamin D receptor for the prevention and treatment of secondary hyperparathyroidism [7, 8].
However, patients with CKD typically exhibit secondary hyperparathyroidism associated with high serum FGF23 levels, which contradicts the ability of FG23 to suppress PTH secretion.
In a previous study, we found that Th2 differentiation was correlated with age and serum vitamin D levels in chronic HD elderly patients, and treatment with activated vitamin D in secondary hyperparathyroidism patients enhanced Th2 differentiation [26].
Rockwell Medical, Inc., a fully-integrated biopharmaceutical company targeting end-stage renal disease (ESRD) and chronic kidney disease (CKD) with products and services for the treatment of iron deficiency, secondary hyperparathyroidism and hemodialysis, has announced the intention to offer shares of its common stock in an underwritten public offering.
Washington, November 5 ( ANI ): Cinacalcet - a drug commonly prescribed to patients with kidney failure and a disturbance of bone and mineral metabolism known as secondary hyperparathyroidism - does not significantly reduce the risk of death or major cardiovascular events, a study led by an international team of researchers has found.
Secondary Hyperparathyroidism (SHPT) is a condition commonly associated with CKD in which the parathyroid glands secrete excessive amounts of PTH.

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