Based on these disappointing results, researchers have turned their focus to mechanisms of secondary brain injury
after hemorrhagic stroke, which play a critical role in the neurological deterioration in these patients [18-20].
Iron overload is involved in secondary brain injury
, leading to neuronal death, brain edema, and neurodeficits after ICH [53, 54].
The company's initial focus is on preventing secondary brain injury
in TBI, a complex process caused by the multiplex biochemical changes which occur upon the primary injury.
This might be explained by multifactorial mechanisms underlying DCI and the development of secondary brain injury
. It further implies SAH and biomarker research aiming at a more comprehensive detection of secondary events after SAH; that one should not focus solely on CVS, but rather on evaluating CVS and DCI.
(7,8) The generalist's role is to co-ordinate this chain of care to prevent secondary brain injury
while identifying patients who will benefit from advanced neurosurgical care.
Secondary brain injury
may follow, exacerbating cerebral dysfunction.
"Making her unconscious meant we were able to protect her airways and stop a secondary brain injury
from lack of oxygen.
Several studies have shown that the timing of surgery is predictive of perioperative hypotension and thus the promotion of secondary brain injury
Using free-radical scavengers to treat brain injuries was the subject of a recent meeting organized by the Brain Injury Association and others interested in the role of free radicals in secondary brain injury
The associated neurologic and vascular damage triggers a chain of events that lead to a secondary brain injury
(SBI), a preventable cause of adverse neurological outcomes.
Secondary brain injury
is the leading cause of hospital deaths after TBI.
The formation of hematoma after the occurrence of acute cerebral hemorrhage can promote the release of a large amount of inflammatory factors and inflammatory mediators which participate in secondary brain injury
that is the key factor influencing the prognosis of patients.17 TNF-[alpha], IL-8 and hs-CRP as the important regulatory factors in inflammatory reaction and immune response plays important roles in the occurrence of secondary brain injury
induced by intracranial hemorrhage.18