secondary adrenal insufficiency


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Related to secondary adrenal insufficiency: tertiary adrenal insufficiency, Acute Adrenal Insufficiency

secondary adrenal insufficiency

Insufficient stimulation of the adrenal glands caused by failure of the pituitary gland to secrete adrenocorticotropic hormone. In this disorder, cortisol levels are reduced, but aldosterone secretion, which is governed by the renin-angiotensin-aldosterone system, is preserved. This differs from primary adrenal insufficiency or Addison disease in which the adrenal glands secrete neither cortisol nor aldosterone.
See also: insufficiency
References in periodicals archive ?
The secondary adrenal insufficiency was treated with dexamethasone resulting in gradual improvement of his nausea, vomiting and headache.
The hypothalamic-pituitary-adrenocortical axis suppression and primary and secondary adrenal insufficiency has been reported in severe falciparum malaria (10).
Patients with primary adrenal insufficiency do not produce cortisol during the 48- to 72-hour period; however, patients with secondary adrenal insufficiency have adequate responses to the test on the second or third day.
If secondary adrenal insufficiency is the cause, doctors may use different imaging tools to reveal the size and shape of the pituitary gland.
Hormonal investigations revealed hypopituitarism in the form of GH deficiency, central hypothyroidism, secondary adrenal insufficiency, secondary hypogonadism with hyperprolactinemia; the skull x- ray and standard sellar computed tomography (CT) were normal (9).
Secondary adrenal insufficiency: The two hypopituitary patients had depressed serum F and E concentrations that responded to short-acting Synacthen stimulation 1 h later.
In the literature, there are a few adult cases who developed ICS and secondary adrenal insufficiency associated with TS [1, 4, 5].
In this review, it was reported that the suppression of the HPA and secondary adrenal insufficiency in children group was more prominent than in adult group because of multiple risk factors written above [7].
The complications related to the treatment of 26 patients included secondary adrenal insufficiency in 3 patients (8.8%), primary adrenal insufficiency 3 in patients (8.8%) and central hypothyroidism in 4 patients (11.7%).