second-line drug

second-line drug

Any therapeutic agent that is not the drug of choice, or the 1st normally used to treat a particular condition; in rheumatoid arthritis, 2nd-line agents are used when standard 'first-line' therapy–ie, anti-inflammatory agents and corticosteroids fail
References in periodicals archive ?
Duo-Cotexcin is normally used as a second-line drug in the treatment of malaria in the country.
Molecular detection of mutations associated with first-and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.
0 assay for second-line drug resistance detection of Mycobacterium tuberculosis isolates in South Africa.
The other rapid diagnostic test to identify second-line drug resistance, which is "the most reliable way to rule out resistance to second-line drugs is a newly recommended diagnostic test for use in national TB reference laboratories.
Current guidelines recommend digoxin as first-line therapy in patients who aren't physically active and as a second-line drug for more active patients.
Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.
National Institute for Health and Care Excellence (NICE) cite sulfonylurea drugs as the top second-line drug treatment for patients with type 2 diabetes if monotherapy with metformin fails.
In the public sector, a large fraction of patients with drug-resistant TB do not get adequate drug-susceptibility testing and second-line drug treatment.
reported the evaluation of NRA for ofloxacin, a second-line drug, and found complete agreement with the agar PM (30).
Losing the fluoroquinolones means we are losing a potent and minimally toxic option for second-line drug therapy.
We are using it for our hospice patients as a second-line drug.
The purpose of our study was to determine whether using a second-line drug resulted in fewer treatment failures in a recurrent otitis episode following an episode of apparent resistance.