second-line


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second-line

(sĕk′ənd-lĭn′)
adj.
1. Relating to or being a secondary stage of something: the body's second-line defense against infection.
2. Being a drug or therapy that is used to treat a condition or disease only after another drug or therapy has been used or considered.
References in periodicals archive ?
"In the updated data from the second-line cohort, we believe ripretinib has demonstrated encouraging clinical benefit based on the objective response rate, disease control rate and median progression free survival rates observed," said Steve Hoerter, CEO of Deciphera.
This is the first study to compare how each of the six major second-line drugs impacts cardiovascular outcomes in Type 2 diabetes patients taking second diabetes medication.
It showed that of the 22,956 individuals given second-line treatment, only 8.2% had claims evidence of recommended use of metformin in the previous 60 days.
Health care company Bayer reported on Thursday the receipt of approval from the US Food and Drug Administration (FDA) for Stivarga (regorafenib) tablets for the second-line treatment of patients with hepatocellular carcinoma (HCC), the most common form of liver cancer.
The shorter regimen is recommended for patients diagnosed with uncomplicated MDR-TB, for example those individuals whose MDR-TB is not resistant to the most important drugs used to treat MDR-TB (fluoroquinolones and injectables), known as "second-line drugs".
Because the original study focused on patients without previous use of second-line drugs, both the STREAM trial and countries that are adopting the 9-month regimen exclude patients who have baseline resistance to fluoroquinolones or a second-line injectable drug.
Patients eligible for our analysis received second-line therapies according to physician discretion and were treated until progression, toxicity, physician discretion or death.
Clinicians always should start with first- and second-line therapies to reduce symptoms of OAB, Dr.
High rate of virological resuppression among patients failing second-line antiretroviral therapy following enhanced adherence support: A model of care in Khayelitsha, South Africa.
A Medecins Sans Frontieres (MSF) report highlights how South Africa's current patent policy is stopping vital second-line HIV drugs from reaching those who can't afford them.
We are proud to deliver on a commitment we made through an announcement with President Clinton [in 2009] to lower the price of second-line treatments for patients with drug-resistant HIV in developing countries" says Mylan president Heather Bresch.
The samples were first analyzed through microscopy by technicians with a second-line analysis by the rats.