second-generation cephalosporin


Also found in: Dictionary, Thesaurus, Encyclopedia.

second-generation cephalosporin

Any of a group of cephalosporin antibiotics possessing some ability to kill gram-positive cocci such as staphylococci and streptococci, as well as aerobic gram-negative rods. Some agents, i.e., cefotetan, cefoxitin, and cefmetazole, can be used to treat anaerobic infections. Examples of second-generation cephalosporins are cefamandole, cefuroxime, cefonicid, ceforanide, cefixime, cefaclor, cefoxitin, cefotetan, and cefmetazole.
See also: cephalosporin
References in periodicals archive ?
Michigan's prior authorization list, for example, allows second-generation cephalosporin antibiotics Cefaclor, Cefaclor ER, Ceftin, Cefzil, Ceptaz, and Rocephin without prior authorization, while Ceclor CD, Ceclor, Cefotan, and Lorabid must receive authorization.
Of the 178 patients treated with a regimen based on recommendations issued by the American Thoracic Society and by a Canadian panel, 105 received a second-generation cephalosporin, 59 got trimethoprim-sulfamethoxazole, 12 received amoxicillin plus clavulanate, and 2 were treated with a macrolide.
Cefprozil (Cefzil) is a second-generation cephalosporin with a broad range of activity against both gram-positive and gram-negative organisms.
The second-line regimen is a second-generation cephalosporin, such as cefuroxime, plus a macrolide if needed, or amoxicillin-clavulanic acid plus a macrolide if needed.