second messenger


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sec·ond mes·sen·ger

an intermediary molecule that is generated as a consequence of hormone-receptor interaction, for example, see adenosine 3',5'-cyclic monophosphate, guanosine 3',5'-cyclic monophosphate, calcium, inositide.
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References in periodicals archive ?
[17.] Berridge MJ (1987) Inositol trisphosphate and diacylglycerol: two interacting second messengers. Annu Rev Biochem 56: 159-193.
The data presented in this report show that calcium acting as a second messenger mimics the response to light and is the likely mechanism of light signal propagation.
This may be due to changes in drug-target interactions, target numbers, or altered second messenger and downstream actions.
Metabotropic receptors: Receptors for neurotransmitters that indirectly lead to the opening of ion channels via second messengers. Binding of the neurotransmitter to the receptor activates G -proteins, which in turn induce the production of second messengers such as cyclic AMP (cAMP) that then activate kinases, ultimately resulting in the opening of ion channels in the cell's membrane.
After interaction with the appropriate receptor, cholinergic stimulation (parasympathetic) via a [Ca.sup.++]-mediated second messenger system causes saliva production in both the parotid and submandibular glands and enzymatic secretion in the parotid glands.
"Earle Hyman is working on Tiresias, and Ruby Dee is the second messenger."
To my knowledge, as described in my appendix which follows, NO exerts its effects through the intracellular second messenger cGMP, and therefore the two substances act through one and the same mechanism.
An initial neurotransmitter will activate the fast ion channel receptor, while a second or third neurotransmitter will activate the second messenger system that modifies the effect of the initial transmitter.
The Second Messenger, a Theban who reports the immediate results of the shepherd's revelation: Jocasta has hanged herself and Oedipus blinded himself with the brooches which fastened her robe.
Goettingen, Germany, May 19, 2016 --(PR.com)-- Cyclic AMP is an essential second messenger for many cellular processes.