scopolamine


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scopolamine

 [sko-pol´ah-mēn]
an anticholinergic and antimuscarinic alkaloid derived from various plants, having a depressant effect on the central nervous system. Used as an antisialagogue preanesthetic medication and as an adjunct to general anesthesia, administered parenterally; as an antiemetic, administered orally or parenterally; and as a cycloplegic and mydriatic, applied topically to the conjunctiva. Called also hyoscine.

sco·pol·a·mine

(skō-pol'ă-mēn, -min),
An alkaloid found in the leaves and seeds of Hyoscyamus niger, Duboisia myoproides, Scopolia japonica, S. carniolica, Atropa belladonna, and other solanaceous plants; exerts anticholinergic actions similar to that of atropine, but is thought to have greater central nervous system effects; useful in preventing motion sickness; available as various salts.
Synonym(s): hyoscine

scopolamine

/sco·pol·a·mine/ (sko-pol´ah-mēn) an anticholinergic alkaloid obtained from various solanaceous plants; used as the base or the hydrobromide salt as an antiemetic and as the hydrobromide salt as a preanesthetic antisialagogue, adjunct to general anesthesia, and topical mydriatic and cycloplegic.

scopolamine

(skə-pŏl′ə-mēn′, -mĭn)
n.
An alkaloid drug, C17H21NO4, extracted from plants such as henbane and used primarily to treat motion sickness and nausea and to dilate the pupil. Also called hyoscine.

scopolamine

[skōpol′əmēn]
Etymology: Giovanni A. Scopoli, Italian naturalist, 1723-1788
an anticholinergic alkaloid obtained from the leaves and seeds of several solanaceous plants. It is a central nervous system depressant.
indications It is prescribed for prevention of motion sickness and as an antiemetic, a sedative in obstetrics, and a cycloplegic and mydriatic.
contraindications Narrow-angle glaucoma, asthma, myasthenia gravis, obstruction of the genitourinary or GI tract, severe ulcerative colitis, and known hypersensitivity prohibit its use.
adverse effects Among the more serious adverse effects are blurred vision, central nervous system effects, tachycardia, dry mouth, decreased sweating, and hypersensitivity reaction. Also called hyoscine. See also transdermal scopolamine.

scopolamine

®Therapeutics An atropine-like anticholinergic–or antimuscarinic, used in preanesthesia, where CNS depression is desirable, GI tract antispasmodic, to ↑ heart rate, and counteract vasodilation and low BP caused by choline esters Metabolism GI tract absorption,12 metabolized in liver, remainder in kidneys Adverse efects Dry mouth, tachycardia, palpitation, pupillary dilatation, blurring of vision, headache, dry
hot skin

sco·pol·a·mine

(skō-pol'ă-mēn)
An alkaloid found in the leaves and seeds of Hyoscyamus niger, and other solanaceous plants; exerts anticholinergic actions similar to that of atropine, but thought to have greater central nervous system effects; useful in preventing motion sickness; available as various salts.
Synonym(s): hyoscine.

scopolamine

An ATROPINE-like drug used in premedication as a sedative and to dry up respiratory and salivary secretions.

sco·pol·a·mine

(skō-pol'ă-mēn, -min)
An alkaloid found in the leaves and seeds of various plants; exerts anticholinergic actions similar to that of atropine, but is thought to have greater central nervous system effects; useful in preventing motion sickness.
Synonym(s): hyoscine.

scopolamine (skōpol´əmēn),

n an alkaloid found in the leaves and seeds of
Atropa belladonna and other solanaceous plants having an action similar to atropine and used when spasmolytic or antisecretory effects are desired.
scopolamine, transdermal,
brand names: Transderm-Scōp, Transderm-V;
drug class: antiemetic, anticholinergic;
action: competitive antagonism of acetylcholine at receptor sites in the eye, smooth muscle, cardiac muscle, glandular cells; inhibition of vestibular input to the central nervous system (CNS), resulting in inhibition of vomiting reflex;
use: prevention of motion sickness.

scopolamine

an anticholinergic alkaloid derived from various plants, used as the hydrobromide in parasympathetic blockade and as a central nervous system depressant.
References in periodicals archive ?
Influence of chronic treatment with olanzapine, clozapine, and scopolamine on performance of a learned 8-arm radial maze task in rats.
Furthermore, pretreatment with PA for 8 days protected the animals from memory deficits produced by scopolamine and diazepam.
As the scientists expected, the normal rats showed increased roaming when given toluene, amphetamine, or scopolamine.
Symptoms of scopolamine poisoning include increased pulse rate (120 to 150 beats per minute), dilated pupils, disorientation, delirium,
For example, his group still gets hyscyamine and scopolamine - antidotes for motion sickness and nerve gas poisioning - from 9-year- old cultures of henbane.
Motion sickness can often be prevented by a prescribed adhesive patch worn behind the ear, which releases a steady flow of the anti-motion-sickness drug scopolamine.
Some drugs contain scopolamine, an anticholinergic.
Previous treatments with scopolamine, baclofen, valproate, clonazepam, carbamazepine, traditional Chinese herbal medicine, and acupuncture had no effect on his abdominal movements and brought side effects such as drowsiness.
Based on this change, her antipsychotic medication was changed from oral clozapine to intramuscular haloperidol (5mg bid) and scopolamine (0.
Datura plant is one of the most important medical plants in the world for its medical importance, either in the traditional or constitutional medicine as a main resource of Tropanealkaloids; in particular hyoscyamine, scopolamine and atropine.
c) Lavandula spp essential oils may help to reduce levels of superoxide dismutase in scopolamine induced neurotoxicity.