panencephalitis

(redirected from sclerosing panencephalitis)
Also found in: Dictionary, Thesaurus.
Related to sclerosing panencephalitis: Measles encephalitis

panencephalitis

 [pan″en-sef″ah-li´tis]
encephalitis, probably of viral origin, that produces intranuclear or intracytoplasmic inclusion bodies that result in parenchymatous lesions of both the gray and white matter of the brain.

pan·en·ceph·a·li·tis

(pan'en-sef'ă-lī'tis),
A diffuse inflammation of the brain.

panencephalitis

/pan·en·ceph·a·li·tis/ (pan″en-sef″ah-li´tis) encephalitis, probably of viral origin, which produces intranuclear or intracytoplasmic inclusion bodies that result in parenchymatous lesions of both the gray and white matter of the brain.

panencephalitis

(păn′ĕn-sĕf′ə-lī′tĭs)
n.
1. Encephalitis that affects both gray and white matter of the brain, resulting in progressive loss of mental and motor functions.
2. Subacute sclerosing panencephalitis.

panencephalitis

[pan′ənsef′əlī′tis]
Etymology: Gk, pan + enkephale, brain, itis
inflammation of the entire brain characterized by an insidious onset, a progressive course with deterioration of motor and mental functions, and evidence of a viral cause. One example is subacute sclerosing panencephalitis, an uncommon childhood disease thought to be caused by a "slow" latent measles virus after recovery from a previous infection. Most of the patients are younger than 11 years of age, and many more boys than girls are affected. The disease results in ataxia, myoclonus, atrophy, cortical blindness, and mental deterioration. Antiviral drugs, immunosuppressants, and interferon inducers are sometimes administered, but the disease is usually unremitting and fatal.

panencephalitis

Simultaneous inflammation of the gray and white matter. See Subacute sclerosing panencephalitis.

pan·en·ceph·a·li·tis

(pan'en-sef'ă-lī'tis)
A diffuse inflammation of the brain.

panencephalitis

An ENCEPHALITIS involving the grey and white matter simultaneously. A very severe form affecting children is caused by a MYXOVIRUS (subacute sclerosing panencephalitis).

panencephalitis

encephalitis with parenchymatous lesions of both the gray and white matter of the brain.

sclerosing panencephalitis
see old dog encephalitis.
References in periodicals archive ?
DISCUSSION: Subacute sclerosing panencephalitis (SSPE) is a slow virus disease caused by persistent infection by mutant measles virus.
Subacute sclerosing panencephalitis (SSPE) is caused by a mutated measles virus and is characterised by cognitive deterioration, motor decline and myoclonus.
Mitochondrial abnormalities in cortical dendrites from patients with early forms of subacute sclerosing panencephalitis (SSPE).
In Canada, Imunovir(TM) is registered for the treatment of subacute sclerosing panencephalitis.
INTRODUCTION: Subacute sclerosing panencephalitis (SSPE) is a slow progressive degeneration of the central nervous system caused by a persistent defective measles virus infection.
Even patients who experience uncomplicated acute measles have a small risk for developing a devastating neurologic illness, subacute sclerosing panencephalitis, years after their infection.
The disease can also cause a serious brain complication known as subacute sclerosing panencephalitis (SSPE), which is fatal.
There are 2 further rare and latent CNS complications resulting from a preceding measles infection: subacute sclerosing panencephalitis (SSPE) caused by years of viral persistence in a seemingly immunocompetent host, (3) and subacute measles encephalitis (SME), occurring in an immunocompromised host.
Truncations, mutations, and deletions in the cytoplasmic domain of the F protein occur in the persistent measles central nervous system complications (subacute sclerosing panencephalitis and measles inclusion body encephalitis) (25).
Neuroprogressive disease of postinfectious origin: a review of a resurging subacute sclerosing panencephalitis (SSPE).
Scalp electroencephalography (EEG) showed poly spikes suggestive of generalized myoclonic epilepsy and generalized periodic discharges suggestive of Subacute Sclerosing Panencephalitis.