The right coronary artery (RCA) displayed a tumorous lesion consisting of severe inflammation and thickening of the adventitia with obliterative phlebitis of venous branches, sclerosing inflammation
of the media, and an increased infiltrate of IgG4-positive plasma cells by immunohistochemistry.
(4.) Sahlin S, Lignell B, Williams M, Dastmalchi M, Orrego A .Treatment of idiopathic sclerosing inflammation
of the orbit (myositis) with infliximab .
Although there are indications that a close relationship between RDD and IgG4 sclerosing inflammation
may exist, a definitive link between RDD and IgG4 positivity has yet to be established.
Histopathologic evaluation of the biopsies revealed the classic findings of idiopathic sclerosing inflammation
. (1) Most of the lesion's volume (more than 90%) was composed of fibrosclerosis; only a small portion consisted microscopically of widely separated lymphoid aggregates or lightly dispersed inflammatory cells.