sclerocornea

sclerocornea

 [skle″ro-kor´ne-ah]
the sclera and cornea regarded as one.

scle·ro·cor·ne·a

(sklē'rō-kōr'nē-ă), [MIM*181700, MIM*269400]
1. The cornea and sclera regarded as forming together the hard outer coat of the eye, the fibrous tunic of the eye.
2. A congenital anomaly in which the whole or part of the cornea is opaque and resembles the sclera; other ocular abnormalities are frequently present.

scle·ro·cor·ne·a

(skler'ō-kōr'nē-ă)
1. The cornea and sclera regarded as forming together the hard outer coat of the eye, the fibrous tunic of the eye.
2. A congenital anomaly in which the whole or part of the cornea is opaque and resembles the sclera; other ocular abnormalities are frequently present.

sclerocornea 

A rare, congenital condition in which the sclera and cornea are considered as a single layer. The limbus is ill defined and portions of opaque scleral tissue with conjunctival vessels cover the cornea. The condition is usually bilateral and frequently associated with cornea plana. Visual acuity is reduced and often it is merely light perception if the entire cornea is involved. The eye is usually hyperopic. Systemic associations include mental retardation, deafness and craniofacial abnormalities. Treatment includes correction of the refractive error but in cases of central corneal opacification keratoplasty may be indicated.
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References in periodicals archive ?
Genetic eye disease spans developmental eye defects such as structural globe anomalies (microphthalmia, anophthalmia, ocular coloboma), anterior segment dysgenesis (including aniridia and sclerocornea), congenital cataracts, primary congenital glaucoma, congenital nystagmus, optic nerve disorders (ranging from hypoplasia to morning glory disc anomaly), to later childhood and adult-onset disorders including corneal and retinal dystrophies, and hereditary optic neuropathies.
These included microcornea (2%), microcornea with iris coloboma (1%), sclerocornea (0.5%), iris coloboma (7%), aniridia (6.5%), ectopia lentis (4%), coloboma of lens (1%), anophthalmos (0.5%) and microphthalmos (1.5%).
###* Persistent fetal vasculature (persistent###* Sclerocornea
Ophthalmologic examination revealed bilateral microphthalmia, sclerocornea, iris and chorioretinal coloboma, blepharophimosis and dacryostenosis (Figure 1a,b).
Other causes include birth trauma, prenatal infections, congenital corneal dystrophies, sclerocornea, metabolic storage diseases, interstitial keratitis, infective keratitis, Peter's anomaly and corneal scarring.
Sclerocornea, hypertelorism, syndactyly, and ambiguous genitalia.
If the concern with clarity is a focal opacity that is peripherally located, think of congenital conditions such as dermoid and sclerocornea, or acquired causes such as bacterial keratitis, the presence of a foreign body, and band keratopathy.
Axenfeld-Reiger syndrome, Peters' anomaly, Alagille syndrome and Sclerocornea. Embryologically, posterior embryotoxon is one of the mesenchymal dysgenesis of the anterior ocular segment caused by the abnormal migration of neural crest cells.
MIDAS###MIDAS syndrome(microphthalmia, dermal aplasia, and sclerocornea).9