sclerema neonatorum


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sclerema

 [sklĕ-re´mah]
induration of the subcutaneous fat.
sclerema adipo´sum (sclerema neonato´rum) diffuse, waxlike hardening of the skin and subcutaneous tissue that occurs in premature and debilitated infants during the first weeks of life, usually associated with an underlying condition such as sepsis, congenital heart disease, respiratory distress, or severe dehydration. As it progresses, the skin becomes cold, mottled, yellow to white, and stony hard. The prognosis is poor if it becomes generalized. Called also edema neonatorum.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

scle·re·ma ne·o·na·to·rum

sclerema appearing at birth or in early infancy, usually in premature and hypothermic infants, as sharply demarcated and yellowish white indurated plaques that usually involve the cheeks, buttocks, shoulders, and calves; subcutaneous fat has a high proportion of saturated fatty acids; microscopically, there is thickening of interlobular fibrous tissue and formation of triglyceride crystals and foreign body giant cells; prognosis is poor for widespread lesions, but localized lesions may resolve slowly over a period of many months.
Farlex Partner Medical Dictionary © Farlex 2012

scle·re·ma ne·o·na·to·rum

(skler-ē'mă nē-ō'nā-tō'rum)
Sclerema appearing at birth or in early infancy, usually in premature and hypothermic infants, as sharply demarcated and yellowish-white indurated plaques that usually involve the cheeks, buttocks, shoulders, and calves; subcutaneous fat has a high proportion of saturated fatty acids; microscopically, there is thickening of interlobular fibrous tissue and formation of triglyceride crystals and foreign body giant cells; prognosis is poor for widespread lesions, but localized lesions may resolve slowly over a period of many months.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Sclerema neonatorum. Report of a case and analysis of subcutaneous and epidermal-dermal lipids by chromatographic methods.
1 Miliaria crystallina 353 95.3 2 Scalp ecchymosis 71 7.1 3 Perianal dermatitis 56 5.6 4 Miliaria rubra 24 2.4 5 Caput succedaneum 9 0.9 6 Sclerema neonatorum 1 0.1 Table XIII.
Sclerema neonatorum is a rare pathological condition usually affecting preterm neonates with high mortality.
Darmstadt, "Sclerema neonatorum: a review of nomenclature, clinical presentation, histological features, differential diagnoses and management," Journal of Perinatology, vol.
Anderson, "Sclerema neonatorum (a study of 16 cases in the special care unit, Mulago Hospital, Kampala)," East African Medical Journal, vol.
Frank, "Sclerema neonatorum. A report of nine cases," Ohio State Medical Journal, vol.
Djojodiguno, "Sclerema neonatorum (literature review)," Paediatrica Indonesiana, vol.
Nielsen, "Sclerema neonatorum; report of a case treated with ACTH," Acta Paediatrica, vol.